Abstract

The CBI Training Program at Texas A&M University was established in 1994. It includes faculty from the Department of Chemistry in the College of Science, the Department of Biochemistry & Biophysics in the College of Agriculture and Life Sciences, and the Department of Medical Biochemistry & Genetics in the College of Medicine. The emphasis is on providing interdisciplinary training to students, with a focus on mechanistic and synthetic approaches. Four new trainees will be added each year and supported for their first two years of graduate study. During this time students carry out laboratory rotations and take formal coursework in mechanistic chemistry, biological chemistry, bioorganic chemistry, molecular biology, and ethics. They also participate in a Chemical Biology journal club throughout their graduate careers. Students are admitted through and receive degrees from either the Department of Chemistry or the Department of Biochemistry & Biophysics; the requirements of the CBI program are compatible with the degree requirements of both departments. ? ? ?

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM008523-10A1
Application #
6751789
Study Section
Special Emphasis Panel (ZGM1-BRT-0 (04))
Program Officer
Rogers, Michael E
Project Start
1994-09-30
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
10
Fiscal Year
2004
Total Cost
$134,479
Indirect Cost

  Institution

Name
Texas A&M University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
078592789
City
College Station
State
TX
Country
United States
Zip Code
77845

  Publications

Iyer, Lavanya K; Sacha, Gregory A; Moorthy, Balakrishnan S et al. (2016) Process and Formulation Effects on Protein Structure in Lyophilized Solids Using Mass Spectrometric Methods. J Pharm Sci 105:1684-1692
Morales, Krystal A; Igumenova, Tatyana I (2012) Synergistic effect of Pb(2+) and phosphatidylinositol 4,5-bisphosphate on C2 domain-membrane interactions. Biochemistry 51:3349-60
Morales, Krystal A; Lasagna, Mauricio; Gribenko, Alexey V et al. (2011) Pb2+ as modulator of protein-membrane interactions. J Am Chem Soc 133:10599-611
Lindahl, Paul A; Holmes-Hampton, Gregory P (2011) Biophysical probes of iron metabolism in cells and organelles. Curr Opin Chem Biol 15:342-6
Srinivasan, Divyamani; Muthukrishnan, Nandhini; Johnson, Gregory A et al. (2011) Conjugation to the cell-penetrating peptide TAT potentiates the photodynamic effect of carboxytetramethylrhodamine. PLoS One 6:e17732
Bethel, Ryan D; Singleton, Michael L; Darensbourg, Marcetta Y (2010) The modular assembly of clusters is the natural synthetic strategy for the active site of [FeFe] hydrogenase. Angew Chem Int Ed Engl 49:8567-9
Angeles-Boza, Alfredo M; Erazo-Oliveras, Alfredo; Lee, Ya-Jung et al. (2010) Generation of endosomolytic reagents by branching of cell-penetrating peptides: tools for the delivery of bioactive compounds to live cells in cis or trans. Bioconjug Chem 21:2164-7
Lee, Ya-Jung; Erazo-Oliveras, Alfredo; Pellois, Jean-Philippe (2010) Delivery of macromolecules into live cells by simple co-incubation with a peptide. Chembiochem 11:325-30
Garber Morales, Jessica; Holmes-Hampton, Gregory P; Miao, Ren et al. (2010) Biophysical characterization of iron in mitochondria isolated from respiring and fermenting yeast. Biochemistry 49:5436-44
Jenkins, Roxanne M; Singleton, Michael L; Leamer, Lauren A et al. (2010) Orientation and stereodynamic paths of planar monodentate ligands in square planar nickel N2S complexes. Inorg Chem 49:5503-14

Showing the most recent 10 out of 72 publications