Abstract

Public Health Relevance

Awarded Narrative The Program in Biomolecular Pharmacology at Boston University is designed to train predoctoral students in pharmacological research and discovery, combining the fundamental principles of pharmacology with novel approaches drawn from bioinformatics, biophysics, biochemistry, biomedical engineering, chemistry, genetics, molecular medicine and neuroscience. Trainees undertake an integrated curriculum that emphasizes translation of rigorous basic science research and acquisition of scientific skills for careers in academia, government or the private sector.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
3T32GM008541-23S1
Application #
10156172
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Koduri, Sailaja
Project Start
1997-07-01
Project End
2023-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
23
Fiscal Year
2020
Total Cost
Indirect Cost

  Institution

Name
Boston University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118

  Publications

Li, Zhuting; Cogswell, Meaghan; Hixson, Kathryn et al. (2018) Nuclear Respiratory Factor 1 (NRF-1) Controls the Activity Dependent Transcription of the GABA-A Receptor Beta 1 Subunit Gene in Neurons. Front Mol Neurosci 11:285
Frame, Alissa A; Wainford, Richard D (2018) Mechanisms of altered renal sodium handling in age-related hypertension. Am J Physiol Renal Physiol 315:F1-F6
Anderson, Nicole M; Mucka, Patrick; Kern, Joseph G et al. (2018) The emerging role and targetability of the TCA cycle in cancer metabolism. Protein Cell 9:216-237
Robinson, Amy A; Abraham, Carmela R; Rosene, Douglas L (2018) Candidate molecular pathways of white matter vulnerability in the brain of normal aging rhesus monkeys. Geroscience 40:31-47
Apicco, Daniel J; Ash, Peter E A; Maziuk, Brandon et al. (2018) Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo. Nat Neurosci 21:72-80
Tararina, Margarita A; Xue, Song; Smith, Lauren C et al. (2018) Crystallography Coupled with Kinetic Analysis Provides Mechanistic Underpinnings of a Nicotine-Degrading Enzyme. Biochemistry 57:3741-3751
Huiting, L N; Samaha, Y; Zhang, G L et al. (2018) UFD1 contributes to MYC-mediated leukemia aggressiveness through suppression of the proapoptotic unfolded protein response. Leukemia :
Zhang, Xiaoling; Frame, Alissa A; Williams, Jonathan S et al. (2018) GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study. Physiol Genomics 50:724-725
Ray, Leah C; Das, Debasis; Entova, Sonya et al. (2018) Membrane association of monotopic phosphoglycosyl transferase underpins function. Nat Chem Biol 14:538-541
Weinstein, Zohar B; Kuru, Nurdan; Kiriakov, Szilvia et al. (2018) Modeling the impact of drug interactions on therapeutic selectivity. Nat Commun 9:3452

Showing the most recent 10 out of 129 publications