Abstract

This proposal requests continuing support for a Cellular, Biochemical, and Molecular Sciences (CBMS) training program at Vanderbilt University. We describe (1) a group of 100 faculty from biomedical research departments at Vanderbilt and our Alliance partner, Meharry Medical College, who are actively engaged in CBMS research, (2) a mechanism involving the Vanderbilt Interdisciplinary Graduate Program (IGP) for recruiting and identifying high caliber trainees, and (3) extraordinary institutional support for CBMS students and faculty. The training program utilizes broad didactic, interdisciplinary training in CBMS target areas, rigorous, elective courses for specialized training, weekly journal club meetings, an annual research retreat, and most importantly, in depth, laboratory research experience. Over the past several years, we have been remarkably successful recruiting excellent students into the IGP and the CBMS training program, particularly students from groups underrepresented in science. Many of the administrative and programmatic initiatives over the past years have contributed to this success and bode well for continuing success.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008554-14
Application #
7647428
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Zatz, Marion M
Project Start
1995-07-01
Project End
2011-06-30
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
14
Fiscal Year
2009
Total Cost
$348,113
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Means, Anna L; Freeman, Tanner J; Zhu, Jing et al. (2018) Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. Cell Mol Gastroenterol Hepatol 6:257-276
Funkhouser-Jones, Lisa J; van Opstal, Edward J; Sharma, Ananya et al. (2018) The Maternal Effect Gene Wds Controls Wolbachia Titer in Nasonia. Curr Biol 28:1692-1702.e6
Steiner, Bradley D; Eberly, Allison R; Hurst, Melanie N et al. (2018) Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli. J Membr Biol 251:65-74
Lojek, Lisa J; Farrand, Allison J; Weiss, Andy et al. (2018) Fur regulation of Staphylococcus aureus heme oxygenases is required for heme homeostasis. Int J Med Microbiol 308:582-589
Norris, Stephen R; Jung, Seungyeon; Singh, Prashant et al. (2018) Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters. Nat Commun 9:2659
Petersen, Christine P; Meyer, Anne R; De Salvo, Carlo et al. (2018) A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach. Gut 67:805-817
Engevik, Amy C; Kaji, Izumi; Engevik, Melinda A et al. (2018) Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. Gastroenterology 155:1883-1897.e10
Snider, Chloe E; Willet, Alaina H; Chen, Jun-Song et al. (2017) Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis. J Cell Biol 216:3041-3050
LePage, Daniel P; Metcalf, Jason A; Bordenstein, Sarah R et al. (2017) Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility. Nature 543:243-247
Hardbower, Dana M; Asim, Mohammad; Luis, Paula B et al. (2017) Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications. Proc Natl Acad Sci U S A 114:E751-E760

Showing the most recent 10 out of 137 publications