Abstract

This proposal is a resubmission requesting continuing support for the Cellular, Biochemical, and Molecular Sciences (CBMS) training program at Vanderbilt University. Over the 15 years of the CBMS training program at Vanderbilt and continuing with the 5-year period preceding this competitive renewal, we have been remarkably successful recruiting excellent students, particularly students from groups underrepresented in science. Extensive institutional support and commitment along with a number of administrative and programmatic initiatives over the past years have contributed to this success and bode well for continuing success. Overall, the CBMS training program encompasses a group of ~80 faculty from biomedical research departments and programs at Vanderbilt that has trained 70 students including 9 current trainees. High caliber trainees are recruited as part of the Vanderbilt Interdisciplinary Graduate Program (IGP) and undergo broad didactic interdisciplinary training in CBMS target areas, rigorous elective courses for specialized training, a weekly journal club meeting, weekly mentoring and training sessions, an annual research retreat, continuing training in Responsible Conduct in Research and, most importantly, in depth, laboratory research experience.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008554-19
Application #
8692426
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Gindhart, Joseph G
Project Start
1995-07-01
Project End
2016-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
19
Fiscal Year
2014
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Biochemistry
Type
Schools of Medicine
DUNS #
City
Nashville
State
TN
Country
United States
Zip Code
37212

  Publications

Norris, Stephen R; Jung, Seungyeon; Singh, Prashant et al. (2018) Microtubule minus-end aster organization is driven by processive HSET-tubulin clusters. Nat Commun 9:2659
Petersen, Christine P; Meyer, Anne R; De Salvo, Carlo et al. (2018) A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach. Gut 67:805-817
Engevik, Amy C; Kaji, Izumi; Engevik, Melinda A et al. (2018) Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes. Gastroenterology 155:1883-1897.e10
Means, Anna L; Freeman, Tanner J; Zhu, Jing et al. (2018) Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. Cell Mol Gastroenterol Hepatol 6:257-276
Funkhouser-Jones, Lisa J; van Opstal, Edward J; Sharma, Ananya et al. (2018) The Maternal Effect Gene Wds Controls Wolbachia Titer in Nasonia. Curr Biol 28:1692-1702.e6
Steiner, Bradley D; Eberly, Allison R; Hurst, Melanie N et al. (2018) Evidence of Cross-Regulation in Two Closely Related Pyruvate-Sensing Systems in Uropathogenic Escherichia coli. J Membr Biol 251:65-74
Lojek, Lisa J; Farrand, Allison J; Weiss, Andy et al. (2018) Fur regulation of Staphylococcus aureus heme oxygenases is required for heme homeostasis. Int J Med Microbiol 308:582-589
Snider, Chloe E; Willet, Alaina H; Chen, Jun-Song et al. (2017) Phosphoinositide-mediated ring anchoring resists perpendicular forces to promote medial cytokinesis. J Cell Biol 216:3041-3050
LePage, Daniel P; Metcalf, Jason A; Bordenstein, Sarah R et al. (2017) Prophage WO genes recapitulate and enhance Wolbachia-induced cytoplasmic incompatibility. Nature 543:243-247
Hardbower, Dana M; Asim, Mohammad; Luis, Paula B et al. (2017) Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications. Proc Natl Acad Sci U S A 114:E751-E760

Showing the most recent 10 out of 137 publications