The University of North Carolina Molecular and Cellular Biophysics Training Program (PMCB) is an interdisciplinary graduate training program with three essential aims: 1. to attract talented post-graduate students to apply the methods and concepts of the quantitative and mathematical sciences to problems in biology. 2. to provide a flexible vehicle for training this diverse group of graduate students who share with our biophysics faculty a commitment to developing molecular level descriptions of complex biological systems and processes. 3. to foster interactions and enhance the training and research environment within this diverse group of faculty and students. The PMCB continues to excel in meeting all three Aims, and most recently has expanded its focus to establish with the Biophysical Society a Summer Course in Biophysics designed to attract talented minority undergraduate students to the field as well. Significant changes in the organization of science graduate programs at UNC have necessitated changes in our Program as well and have led to plans for a PhD degree program in biophysics at UNC. This application is for continued funding of our successful training efforts and in support our efforts to move forward in these new areas.
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| Kirkpatrick, Christine L; Parsley, Nicole C; Bartges, Tessa E et al. (2018) Exploring bioactive peptides from bacterial secretomes using PepSAVI-MS: identification and characterization of Bac-21 from Enterococcus faecalis pPD1. Microb Biotechnol 11:943-951 |
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| Patteson, Jon B; Cai, Wenlong; Johnson, Rachel A et al. (2018) Identification of the Biosynthetic Pathway for the Antibiotic Bicyclomycin. Biochemistry 57:61-65 |
| Stadmiller, Samantha S; Pielak, Gary J (2018) The Expanding Zoo of In-Cell Protein NMR. Biophys J 115:1628-1629 |
| Parsley, Nicole C; Kirkpatrick, Christine L; Crittenden, Christopher M et al. (2018) PepSAVI-MS reveals anticancer and antifungal cycloviolacins in Viola odorata. Phytochemistry 152:61-70 |
| McLamarrah, Tiffany A; Buster, Daniel W; Galletta, Brian J et al. (2018) An ordered pattern of Ana2 phosphorylation by Plk4 is required for centriole assembly. J Cell Biol 217:1217-1231 |
| Hayne, Cassandra K; Yumerefendi, Hayretin; Cao, Lin et al. (2018) We FRET so You Don't Have To: New Models of the Lipoprotein Lipase Dimer. Biochemistry 57:241-254 |
| Guseman, Alex J; Perez Goncalves, Gerardo M; Speer, Shannon L et al. (2018) Protein shape modulates crowding effects. Proc Natl Acad Sci U S A 115:10965-10970 |
| Kudlacek, Stephan T; Premkumar, Lakshmanane; Metz, Stefan W et al. (2018) Physiological temperatures reduce dimerization of dengue and Zika virus recombinant envelope proteins. J Biol Chem 293:8922-8933 |
| Studer, Sabine; Hansen, Douglas A; Pianowski, Zbigniew L et al. (2018) Evolution of a highly active and enantiospecific metalloenzyme from short peptides. Science 362:1285-1288 |
Showing the most recent 10 out of 96 publications
