The primary purpose of this broadly based multidisciplinary Training Program is to prepare students for biomedical research careers in schools of medicine, dentistry and pharmacy, in research institutes, and in government or industrial laboratories. A major goal is to provide trainees with a program in which they will be represented by the 35 training faculty include transmembrane signaling, cell growth control and molecular recognition, substance abuse, and molecular toxicology. Training faculty represent 11 departments and three Centers at Emory. The most important component of training is laboratory research, first as a series of three research rotations, then in the dissertation laboratory. This training is complemented by core courses in pharmacology that emphasize quantitative analysis of drug action, including receptor structure and function, courses in biochemistry/molecular biology and biostatistics, and advanced courses in specialty areas; by seminar courses and by journal clubs. Emphasis throughout is placed on oral presentation skills; students make formal oral presentations of their own work or that in the literature on numerous occasions before their dissertation defense. The Program is designed to support six students each year from a total population of about 25 eligible students. The student who completes the predoctoral training program will have acquired broad familiarity with pharmacology, knowledge in depth in the area of dissertation research, the ability to search, read critically and report on the literature of the biomedical sciences, mastery of a variety of laboratory techniques useful in modern biomedical research, skill in planning and executing a research project, ability to write clear, accurate scientific reports for publication, and ability to present effectively the results of research. A large percentage of the previous trainees of the core faculty have obtained postdoctoral training and then secured desirable positions in academic or industrial institutions; they continue to be productive in biomedical sciences.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM008602-09
Application #
6792175
Study Section
National Institute of General Medical Sciences Initial Review Group (BRT)
Program Officer
Preusch, Peter C
Project Start
1996-07-01
Project End
2006-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
9
Fiscal Year
2004
Total Cost
$197,027
Indirect Cost
Name
Emory University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
066469933
City
Atlanta
State
GA
Country
United States
Zip Code
30322
Hudson, William H; Vera, Ian Mitchelle S de; Nwachukwu, Jerome C et al. (2018) Cryptic glucocorticoid receptor-binding sites pervade genomic NF-?B response elements. Nat Commun 9:1337
Brown, Harrison C; Zakas, Philip M; George, Stephan N et al. (2018) Target-Cell-Directed Bioengineering Approaches for Gene Therapy of Hemophilia A. Mol Ther Methods Clin Dev 9:57-69
Gibb, Alasdair J; Ogden, Kevin K; McDaniel, Miranda J et al. (2018) A structurally derived model of subunit-dependent NMDA receptor function. J Physiol 596:4057-4089
Collins, Jeffrey M; Walker, Douglas I; Jones, Dean P et al. (2018) High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans. PLoS One 13:e0205398
Hansen, Kasper B; Yi, Feng; Perszyk, Riley E et al. (2018) Structure, function, and allosteric modulation of NMDA receptors. J Gen Physiol 150:1081-1105
Gurbani, Saumya S; Schreibmann, Eduard; Maudsley, Andrew A et al. (2018) A convolutional neural network to filter artifacts in spectroscopic MRI. Magn Reson Med 80:1765-1775
Hu, Xin; Chandler, Joshua D; Orr, Michael L et al. (2018) Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice. J Nutr 148:675-684
Flynn, Autumn R; Mays, Suzanne G; Ortlund, Eric A et al. (2018) Development of Hybrid Phospholipid Mimics as Effective Agonists for Liver Receptor Homologue-1. ACS Med Chem Lett 9:1051-1056
Gerber, Kyle J; Squires, Katherine E; Hepler, John R (2018) 14-3-3? binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:G?i-AlF4- signaling complex and RGS14 nuclear localization. J Biol Chem 293:14616-14631
Raikar, Sunil S; Fleischer, Lauren C; Moot, Robert et al. (2018) Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines. Oncoimmunology 7:e1407898

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