Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
1T32GM008613-01
Application #
2168459
Study Section
Special Emphasis Panel (ZGM1-GBD-2)
Project Start
1996-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Genetics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Meier, Ingo D; Walker, Michael P; Matera, A Gregory (2018) Gemin4 is an essential gene in mice, and its overexpression in human cells causes relocalization of the SMN complex to the nucleoplasm. Biol Open 7:
Nguyen, Hieu T; Hinman, Melissa N; Guo, Xuan et al. (2017) Neurofibromatosis type 1 alternative splicing is a key regulator of Ras/ERK signaling and learning behaviors in mice. Hum Mol Genet 26:3797-3807
Zentner, Gabriel E; Balow, Stephanie A; Scacheri, Peter C (2014) Genomic characterization of the mouse ribosomal DNA locus. G3 (Bethesda) 4:243-54
Hinman, Melissa N; Sharma, Alok; Luo, Guangbin et al. (2014) Neurofibromatosis type 1 alternative splicing is a key regulator of Ras signaling in neurons. Mol Cell Biol 34:2188-97
Hinman, Melissa N; Zhou, Hua-Lin; Sharma, Alok et al. (2013) All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing. Nucleic Acids Res 41:5049-61
Balow, Stephanie A; Pierce, Lain X; Zentner, Gabriel E et al. (2013) Knockdown of fbxl10/kdm2bb rescues chd7 morphant phenotype in a zebrafish model of CHARGE syndrome. Dev Biol 382:57-69
Zentner, Gabriel E; Saiakhova, Alina; Manaenkov, Pavel et al. (2011) Integrative genomic analysis of human ribosomal DNA. Nucleic Acids Res 39:4949-60
Chou, Shih-Wei; Hwang, Philsang; Gomez, Gustavo et al. (2011) Fascin 2b is a component of stereocilia that lengthens actin-based protrusions. PLoS One 6:e14807
Zhou, Hua-Lin; Hinman, Melissa N; Barron, Victoria A et al. (2011) Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner. Proc Natl Acad Sci U S A 108:E627-35
Johnson, Matthew L; Nagengast, Alexis A; Salz, Helen K (2010) PPS, a large multidomain protein, functions with sex-lethal to regulate alternative splicing in Drosophila. PLoS Genet 6:e1000872

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