The goal of this training program is to prepare young investigators to perform clinically applicable and translational research in the field of trauma science. The program is based at the Burn and Shock Trauma Institute of Loyola University in Chicago, a unique, highly collaborative research environment that includes more than 40 persons, including eight principal investigators, four additional scientific faculty, six clinical specialists in trauma and critical care, eight post-doctoral fellows (both MDs and Ph.D.s), nine graduate students, two research nurses, five research technicians, and three support staff. The program solicits applications from resident physicians and post-doctoral Ph.D.s who wish to enter a two-year period of intensive research training in the field of traumatology. The program, which has been in place for 31/2 years, currently accepts one new trainee each year, and a goal for the next cycle is to expand the program to include the appointment of two new trainees each year. A specific plan for the recruitment of underrepresented ? minorities, which includes local, regional, and national efforts has been established. Trainees are allowed to freely select from among eight different principal investigators who are each experienced ? mentors in trauma-related research, including 1) myelopoietic alterations after injury, 2) immune changes following burn and sepsis, 3) ethanol consumption and injury outcome, 4) neuroimmune regulation and trauma, and 5) wound healing and vascular repair. The training plan emphasizes a close working relationship between each trainee and their selected mentor, and includes laboratory research, seminars, journal clubs, training in grant writing, and didactic coursework in both statistics and the responsible conduct of research. Written research proposals, formal research presentations, and semi-annual evaluations are required of all trainees. Recognizing that many clinicians find it difficult to sustain independent research efforts, the program emphasizes collaborative linkages between basic scientists and clinicians. To develop an appreciation for clinical problems, Ph.D. trainees participate in selected clinical conferences and attend rounds on the Trauma and Burn Services during defined periods. Our long-term goal is to increase the number of clinicians and Ph.D. scientists who are qualified and motivated to work together to address fundamental questions in translational trauma research. ? ?

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZGM1-BRT-5 (PD))
Program Officer
Somers, Scott D
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Loyola University Chicago
Schools of Medicine
United States
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Cobb, Adrienne N; Eguia, Emanuel; Janjua, Haroon et al. (2018) Put Me in the Game Coach! Resident Participation in High-risk Surgery in the Era of Big Data. J Surg Res 232:308-317
Cannon, Abigail R; Kuprys, Paulius V; Cobb, Adrienne N et al. (2018) Alcohol enhances symptoms and propensity for infection in inflammatory bowel disease patients and a murine model of DSS-induced colitis. J Leukoc Biol 104:543-555
Bruce, William J; Chang, Victor; Joyce, Cara J et al. (2018) Age at Time of Craniosynostosis Repair Predicts Increased Complication Rate. Cleft Palate Craniofac J 55:649-654
Eguia, Emanuel; Hwalek, Ann E; Martin, Brendan et al. (2018) What are the predictors that can help identify safe removal of drains following pancreatectomy? Am J Surg 216:955-958
Cobb, Adrienne N; Daungjaiboon, Witawat; Brownlee, Sarah A et al. (2018) Seeing the forest beyond the trees: Predicting survival in burn patients with machine learning. Am J Surg 215:411-416
Nassoiy, Sean P; Babu, Favin S; LaPorte, Heather M et al. (2018) Effects of the Kv7 voltage-activated potassium channel inhibitor linopirdine in rat models of haemorrhagic shock. Clin Exp Pharmacol Physiol :
Nassoiy, Sean P; Babu, Favin S; LaPorte, Heather M et al. (2018) Pharmacological modulation of C-X-C motif chemokine receptor 4 influences development of acute respiratory distress syndrome after lung ischaemia-reperfusion injury. Clin Exp Pharmacol Physiol 45:16-26
Eguia, Emanuel; Cobb, Adrienne N; Kirshenbaum, Eric J et al. (2018) Racial and Ethnic Postoperative Outcomes After Surgery: The Hispanic Paradox. J Surg Res 232:88-93
Cobb, Adrienne N; Barkat, Adel; Daungjaiboon, Witawat et al. (2018) Carotid Body Tumor Resection: Just as Safe without Preoperative Embolization. Ann Vasc Surg 46:54-59
Cobb, Adrienne N; Erickson, Taylor R; Kothari, Anai N et al. (2018) Commercial quality ""awards"" are not a strong indicator of quality surgical care. Surgery 164:379-386

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