This proposal requests support for the MSTP at the University of Cincinnati College of Medicine (UCCOM). Our dual-degree program was established in 1985 and has been continuously NIH-funded for over 15 years. It enrolls 9 new students each year and currently includes 55 students. The central goal of the UCCOM MSTP is to train physician scientists who will be the leaders in their respective fields in academic medicine. Our Program is supported by a solid infrastructure in clinical and research training. Our students can choose from 10 diverse graduate programs. The success of our Program is best illustrated by the success of our graduates. Of our 94 graduates, 52 (79%) remain in academia or in research intensive careers in industry or government and 32 of these (62%) have research funding from the NIH, industry or government. Alumni from our program are likely to work in full-time academic medicine; 49 or 74% of graduates remain in academic medicine, and notably 29 (59%) of these have NIH funding to support their research. In addition, 3 of our alumni hold leadership positions in government or industry. Our students come from a diverse applicant pool drawn from across the nation. For the class that matriculated in the Fall of 2016, we had 187 applicants from 34 states. Our current MSTP students include 18% URM and 16% disadvantaged/disabled students. The average time to complete our MSTP for the last 10 years is 8.1 years and our students have matched at the most competitive residency programs. Since the last funding period, several important and exciting developments have taken place, which include increases in the size and quality of our applicant pool including URM and disabled/disadvantaged applicants, our program faculty, extramural research support among our program faculty, flexibility in the M3/M4 curriculum for MSTP students, number and breadth of training opportunities for MD/PhD candidates, expansion of both UCCOM and CCHMC facilities, design and implementation of a web-based physician scientist specific individual development plan (IDP), design and implementation of the MSTP Transition Series designed to provide targeted and enhanced guidance at each transition point during MSTP training. We are confident that we can continue to achieve our aims and meet the central goal of our program. Towards this goal, we are requesting support for 10 positions.
The need for investigators who are well trained in both basic science and clinical research has been and continues to be an unmet need. NIGMS Medical Scientist Training Programs (MSTP) were developed to meet the need for more physician scientists and offer unique training opportunities. The UCCOM MSTP has been successful with 79% its graduates in careers consistent with their training as physician scientists.
|Kuerbitz, Jeffrey; Arnett, Melinda; Ehrman, Sarah et al. (2018) Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci 38:1160-1177|
|Wu, Lai Man Natalie; Deng, Yaqi; Wang, Jincheng et al. (2018) Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell 33:292-308.e7|
|Betz, Kristina J; Maier, Elizabeth A; Amarachintha, Surya et al. (2018) Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice. PLoS One 13:e0198434|
|Storr, Helen L; Chatterjee, Sumana; Metherell, Louise A et al. (2018) Non-classical growth hormone insensitivity (GHI): characterization of mild abnormalities of GH action. Endocr Rev :|
|Trisno, Stephen L; Philo, Katherine E D; McCracken, Kyle W et al. (2018) Esophageal Organoids from Human Pluripotent Stem Cells Delineate Sox2 Functions during Esophageal Specification. Cell Stem Cell 23:501-515.e7|
|Owens, A Phillip; Robbins, Nathan; Saum, Keith et al. (2018) Tefillin Use Induces Remote Ischemic Preconditioning Pathways in Healthy Males. Am J Physiol Heart Circ Physiol :|
|Pugh, Amanda M; Giannini, Courtney M; Pinney, Susan M et al. (2018) Characteristics and diagnosis of pregnancy and lactation associated breast cancer: Analysis of a self-reported regional registry. Am J Surg 216:809-812|
|Wulsin, Aynara C; Franco-Villanueva, Ana; Romancheck, Christian et al. (2018) Functional disruption of stress modulatory circuits in a model of temporal lobe epilepsy. PLoS One 13:e0197955|
|Serrano-Lopez, Juana; Nattamai, Kalpana; Pease, Nicholas A et al. (2018) Loss of DEK induces radioresistance of murine restricted hematopoietic progenitors. Exp Hematol 59:40-50.e3|
|Travers, Jared; Rochman, Mark; Miracle, Cora E et al. (2018) Chromatin regulates IL-33 release and extracellular cytokine activity. Nat Commun 9:3244|
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