Anesthesiology's success in making the intraoperative environment an extremely safe place, an accomplishment now recognized and emulated by other specialties, should not obscure the fact that important fundamental questions about the entire perioperative experience remain unanswered. These questions pertain to 1) the mechanism of general anesthetic action, 2) physiology of the perioperative state, 3) the mechanism and prevention of postoperative delirium and cognitive dysfunction, 4) providing safety throughout the entire perioperative period, 5) improving long-term outcomes, and 6) the treatment of acute and chronic pain. However, maintaining the scientific infrastructure that will guide the field of Anesthesiology into the future requires a core of well-trained and motivated physician-scientists within the specialty who are dedicated to the pursuit of problems important to Anesthesiology. To help ensure a scientifically robust future for Anesthesiology, the Department of Anesthesiology and Critical Care Medicine (ACCM) at the Johns Hopkins University is submitting this application to support Postdoctoral Research Training in Anesthesiology. In addition to providing a critical avenue for the support of Trainees, it is anticipated that this program will continue to refine the approach whereby Johns Hopkins ACCM recruits, trains, and develops the next generation of physician-scientists in the specialty of Anesthesiology. ACCM has a long and productive history of providing training in clinical and basic Anesthesiology research, which this Training Program will continue to cultivate and formalize. Positive results are now being realized with the outstanding Trainees currently supported by the Training Program. Combined with the considerable resources already in place for faculty development at Johns Hopkins University, an Anesthesiology Post Doctoral Research Training Grant will continue to provide an outstanding opportunity for training physician-scientists to extend the scientific foundation for the practice of Anesthesiology.

Public Health Relevance

Important fundamental questions exist about anesthesia and the care of patients during and after surgery. The goal of this application is to provide support for the training of physician-scientists to address these important problems and guide the specialty of Anesthesiology into the future.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
5T32GM075774-08
Application #
8487417
Study Section
Special Emphasis Panel (ZGM1-BRT-5 (PD))
Program Officer
Cole, Alison E
Project Start
2006-07-01
Project End
2016-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
8
Fiscal Year
2013
Total Cost
$279,113
Indirect Cost
$18,305
Name
Johns Hopkins University
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Cohen, Steven P; Doshi, Tina L; Constantinescu, Octav C et al. (2018) Effectiveness of Lumbar Facet Joint Blocks and Predictive Value before Radiofrequency Denervation: The Facet Treatment Study (FACTS), a Randomized, Controlled Clinical Trial. Anesthesiology 129:517-535
Maher, Dermot P; Martins, Yuri Chaves; Doshi, Tina et al. (2018) Neuropathic Pain Medication Use Does Not Alter Outcomes of Spinal Cord Stimulation for Lower Extremity Pain. Neuromodulation 21:106-113
Wu, Adela; Doshi, Tina; Hung, Alice et al. (2018) Immediate and Long-Term Outcomes of Microvascular Decompression for Mixed Trigeminal Neuralgia. World Neurosurg 117:e300-e307
Doshi, Tina L; Cohen, Steven P (2018) Cracks in the Case against Epidural Steroids: Examining the Evidence for Vertebral Fracture Risk. Pain Med 19:417-418
Doshi, Tina L; Bicket, Mark C (2018) Why Aren't There More Female Pain Medicine Physicians? Reg Anesth Pain Med 43:516-520
Steffen, Katherine M; Noje, Corina; Costabile, Philomena M et al. (2018) Pediatric Transport Triage: Development and Assessment of an Objective Tool to Guide Transport Planning. Pediatr Emerg Care :
Haileselassie, Bereketeab; Su, Erik; Pozios, Iraklis et al. (2017) Myocardial oxidative stress correlates with left ventricular dysfunction on strain echocardiography in a rodent model of sepsis. Intensive Care Med Exp 5:21
Maher, Dermot P; Chen, Lucy; Mao, Jianren (2017) Intravenous Ketamine Infusions for Neuropathic Pain Management: A Promising Therapy in Need of Optimization. Anesth Analg 124:661-674
Hung, Alice L; Lim, Michael; Doshi, Tina L (2017) Targeting cytokines for treatment of neuropathic pain. Scand J Pain 17:287-293
Maher, Dermot P; Zhang, Yi; Ahmed, Shihab et al. (2017) Chronic Opioid Therapy Modifies QST Changes After Ketamine Infusion in Chronic Pain Patients. J Pain 18:1468-1475

Showing the most recent 10 out of 41 publications