The Medical Science Training Program (MSTP) at the Medical College of Wisconsin (MCW) provides integrated basic science and medical training as the educational foundation for future MD-PhD trained physician scientists. MCW is the third-largest private medical school in the country and ranks in the top third of US medical schools in total NIH funding, and is one of the fastest growing medical schools in the US. MCW has supported MD-PhD training since 1982, and in 2010, MCW received an MSTP T-32 award. There are currently 50 students in the MCW-MSTP. This application is the second renewal of the MCW-MSTP and is submitted by members of the MSTP leadership with greater than 55 years of MD- PhD training experience. The mission of MCW-MSTP is to prepare students for careers as physician- scientists by providing a training experience which allows students to conduct hypothesis-driven research and to obtain the fundamental skills of a physician to practice evidence-based medicine as an MD-PhD. MCW-MSTP welcomes all applicants, including students of diversity, students with disabilities, and students from socio-economically disadvantaged backgrounds. MCW-MSTP strives to exemplify the NIGMS Diversity Statement ?diverse teams working together and capitalizing on innovative ideas and distinct perspectives outperform homogeneous teams.? MCW-MSTP students have training experiences which are stage-specific, including an M1-M2 journal club for vertical integration during preclinical training, committee- and individual- mentoring to identify a PhD mentor and entry into a residency program, and MSTP-specific workshops to develop writing and communications skills in team-based, active-learning sessions. In addition, during graduate school, students conduct clinical activities and participate in a Morning Report series to maintain clinical competency. The Residency Selection Workshop and the Morning Report provide vertical integration between students in graduate school and M3/M4 students. Common activities for MSTP students include: an annual Individual Development Plan for self-assessment of student progress, an annual one-on-one meeting with the Program Director, an annual Retreat, luncheons with physician scientists and MSTP alumni, a Women?s Luncheon series, a Physician-Scientist lecture series, monthly Research in Progress seminars, and twice-a-year refresher Responsible Conduct in Research sessions. During the current funding period, MSTP alumni have shown strong publication and research productivity, with a high percentage of our 15-year alumni and total alumni with NIH research support, and a high percentage of current students with ?F? awards. MCW-MSTP seeks to expand support to eight, one year pre-doctoral positions to align with the positive outcome data.

Public Health Relevance

The Medical Science Training Program (MSTP) at the Medical College of Wisconsin (MCW) provides integrated basic science and medical training as the educational foundation for future academic physician scientists. The mission of MCW-MSTP is to prepare students for careers as physician-scientists, which allows students to conduct hypothesis-driven research and to practice evidence-based medicine as an MD-PhD. MCW-MSTP welcomes all applicants, including students of diversity, students with disabilities, and students from socio-economically disadvantaged backgrounds.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Institutional National Research Service Award (T32)
Project #
2T32GM080202-11
Application #
9793027
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Maas, Stefan
Project Start
2010-07-01
Project End
2025-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
11
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
937639060
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Sadler, Katelyn E; Zappia, Katherine J; O?Hara, Crystal L et al. (2018) Chemokine (c-c motif) receptor 2 mediates mechanical and cold hypersensitivity in sickle cell disease mice. Pain 159:1652-1663
Mammoto, Akiko; Muyleart, Megan; Kadlec, Andrew et al. (2018) YAP1-TEAD1 signaling controls angiogenesis and mitochondrial biogenesis through PGC1?. Microvasc Res 119:73-83
Szpakowska, Martyna; Nevins, Amanda M; Meyrath, Max et al. (2018) Different contributions of chemokine N-terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3. Br J Pharmacol 175:1419-1438
Miller, James J; Aoki, Kazuhiro; Moehring, Francie et al. (2018) Neuropathic pain in a Fabry disease rat model. JCI Insight 3:
Egner, John M; Jensen, Davin R; Olp, Michael D et al. (2018) Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein-Detected NMR Spectroscopy. Chembiochem 19:448-458
Chen, Yao; Zander, Ryan; Khatun, Achia et al. (2018) Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation. Front Immunol 9:2826
Lapierre-Landry, Maryse; Huckenpahler, Alison L; Link, Brian A et al. (2018) Imaging Melanin Distribution in the Zebrafish Retina Using Photothermal Optical Coherence Tomography. Transl Vis Sci Technol 7:4
Thomas, Monica A; Kleist, Andrew B; Volkman, Brian F (2018) Decoding the chemotactic signal. J Leukoc Biol 104:359-374
Newman, Debra K; Fu, Guoping; McOlash, Laura et al. (2018) Frontline Science: PECAM-1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells. J Leukoc Biol 104:883-893
Ait-Aissa, Karima; Kadlec, Andrew O; Hockenberry, Joseph et al. (2018) Telomerase reverse transcriptase protects against angiotensin II-induced microvascular endothelial dysfunction. Am J Physiol Heart Circ Physiol 314:H1053-H1060

Showing the most recent 10 out of 84 publications