This is an application for renewal of the institutional training grant, graduate research training in perinatal biology. The goal, of this interdisciplinary post-doctoral program of the Cardiovascular Research Institute and Departments of Pediatrics and of Obstetrics, Gynecology and Reproductive Science at the University of California San Francisco, is to provide comprehensive training in perinatal science and mentored career development for pediatricians and obstetricians with MD or MD, PhD degrees and who are committed to an academic career with a strong research component. The program provides advanced research training for clinicians in basic laboratory science, clinical investigation or studies in epidemiology, health services or health policy related to maternal, fetal and neonatal illnesses. The key elements of the proposed training are: (1) a mentored research experience, (2) scientific course work, (3) career development workshops, (4) interdisciplinary experiences and (5) continuing review and evaluation. The program is designed to provide 2 to 3 years of advanced research training. A large number of exceptionally well qualified faculty have committed their support as research mentors for this program. All fellows will take courses in Responsible Conduct in Research, Scientific Writing and the Art of Lecturing. Additional course work in the specific field of research will be planned by the fellow and research mentor. Each fellow will be supported by a three member mentoring committee, who will meet regularly (and no less than twice a year) with the fellow to assist in setting and monitoring progress towards research and career goals. Evaluation of the overall program is by a UCSF Advisory Committee and an External Review Board of prominent researchers and mentors. The proposed program is designed to strengthen this program that has an excellent record for 24 years of graduates becoming productive researchers and academic leaders in their respective fields of Maternal-Fetal Medicine and Neonatal-Perinatal Medicine.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
2T32HD007162-26
Application #
6894197
Study Section
Special Emphasis Panel (ZHD1-DSR-A (09))
Program Officer
Raju, Tonse N
Project Start
1990-07-01
Project End
2010-04-30
Budget Start
2005-05-15
Budget End
2006-04-30
Support Year
26
Fiscal Year
2005
Total Cost
$146,395
Indirect Cost
Name
University of California San Francisco
Department
Pediatrics
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Basta, Amaya M; Lusk, Leslie A; Keller, Roberta L et al. (2016) Fetal Stomach Position Predicts Neonatal Outcomes in Isolated Left-Sided Congenital Diaphragmatic Hernia. Fetal Diagn Ther 39:248-55
Lusk, Leslie A; Wai, Katherine C; Moon-Grady, Anita J et al. (2015) Persistence of pulmonary hypertension by echocardiography predicts short-term outcomes in congenital diaphragmatic hernia. J Pediatr 166:251-6.e1
Olson, Emma; Lusk, Leslie A; Fineman, Jeffrey R et al. (2015) Short-Term Treprostinil Use in Infants with Congenital Diaphragmatic Hernia following Repair. J Pediatr 167:762-4
Lusk, Leslie A; Wai, Katherine C; Moon-Grady, Anita J et al. (2015) Fetal ultrasound markers of severity predict resolution of pulmonary hypertension in congenital diaphragmatic hernia. Am J Obstet Gynecol 213:216.e1-8
Lusk, Leslie A; Brown, Erin G; Overcash, Rachael T et al. (2014) Multi-institutional practice patterns and outcomes in uncomplicated gastroschisis: a report from the University of California Fetal Consortium (UCfC). J Pediatr Surg 49:1782-6
Kim, Lena H; Cohan, Deborah L; Sparks, Teresa N et al. (2013) The cost-effectiveness of repeat HIV testing during pregnancy in a resource-limited setting. J Acquir Immune Defic Syndr 63:195-200
Nash, K B; Bonifacio, S L; Glass, H C et al. (2011) Video-EEG monitoring in newborns with hypoxic-ischemic encephalopathy treated with hypothermia. Neurology 76:556-62
Carey, William A; Taylor, Glen D; Dean, Willow B et al. (2010) Tenascin-C deficiency attenuates TGF-ß-mediated fibrosis following murine lung injury. Am J Physiol Lung Cell Mol Physiol 299:L785-93
Potter, Gregory B; Petryniak, Magdalena A; Shevchenko, Eugenia et al. (2009) Generation of Cre-transgenic mice using Dlx1/Dlx2 enhancers and their characterization in GABAergic interneurons. Mol Cell Neurosci 40:167-86
McCulley, David J; Kang, Ji-One; Martin, James F et al. (2008) BMP4 is required in the anterior heart field and its derivatives for endocardial cushion remodeling, outflow tract septation, and semilunar valve development. Dev Dyn 237:3200-9

Showing the most recent 10 out of 40 publications