The primary goal of this training program has been, and is, to attract research oriented individuals from a variety of disciplines and focus their research interests on reproductive sciences. Research and training experiences for graduate students and postdoctoral fellows are planned to: 1) increase their involvement and knowledge in the general field of reproductive sciences; 2) expose them to relevant methods and approaches to research in reproductive biology; and 3) support the development of their research records in a variety of areas of the reproductive sciences to enhance their employment and placement opportunities after completion of their training. A secondary goal is to increase the overall interest and awareness of students and faculty throughout the Texas Tech University (TTU) and the Texas Tech University Health Sciences Center (TTUHSC) in research related to reproductive biology. This secondary goal is considered important to permit extension of the scope of training in this area, beyond the numbers that can be supported directly by this grant (i.e. currently 3 predoctoral and 1 post doctoral trainee). These goals will continue to be accomplished by: 1) recruiting qualified trainees by placing advertisements in journals and at placement centers of professional society meetings; 2) offering a graduate course in Biology of Reproduction which is required of all trainees but is attended by students from outside the program as well; 3) supporting expenses for a series of guest speakers who are recognized experts in various areas related to reproductive biology; 4) holding workshops at which guest speakers can informally discuss broader aspects of their research with faculty and trainees; 5) using our informal reproductive research conference and more formal departmental seminar formats for students to give presentations to their colleagues to sharpen their presentation skills; and 6) supporting trainee travel to obtain research or training experience or to present their work at national meetings.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD007271-18
Application #
6329825
Study Section
Pediatrics Subcommittee (CHHD)
Program Officer
Taymans, Susan
Project Start
1984-09-01
Project End
2004-04-30
Budget Start
2001-05-01
Budget End
2002-04-30
Support Year
18
Fiscal Year
2001
Total Cost
$121,274
Indirect Cost
Name
Texas Tech University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
609980727
City
Lubbock
State
TX
Country
United States
Zip Code
79430
Hsia, Nelson; Brousal, Jeffrey P; Hann, Stephen R et al. (2005) Recapitulation of germ cell- and pituitary-specific expression with 1.6 kb of the cystatin-related epididymal spermatogenic (Cres) gene promoter in transgenic mice. J Androl 26:249-57
Hsia, Nelson; Cornwall, Gail A (2004) DNA microarray analysis of region-specific gene expression in the mouse epididymis. Biol Reprod 70:448-57
Day, Audra; Markwardt, Jody; Delaguila, Rolando et al. (2004) Cell size and Cln-Cdc28 complexes mediate entry into meiosis by modulating cell growth. Cell Cycle 3:1433-9
Hsia, Nelson; Cornwall, Gail A (2003) Cres2 and Cres3: new members of the cystatin-related epididymal spermatogenic subgroup of family 2 cystatins. Endocrinology 144:909-15
Cornwall, Gail A; Cameron, Angus; Lindberg, Iris et al. (2003) The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2. Endocrinology 144:901-8
Wassler, Michael; Syntin, Patrick; Sutton-Walsh, H G et al. (2002) Identification and characterization of cystatin-related epididymal spermatogenic protein in human spermatozoa: localization in the equatorial segment. Biol Reprod 67:795-803
Paz, C; Cornejo Maciel, F; Maloberti, P et al. (2002) Protein tyrosine phosphatases are involved in LH/chorionic gonadotropin and 8Br-cAMP regulation of steroidogenesis and StAR protein levels in MA-10 Leydig cells. J Endocrinol 175:793-801
Eubank, D W; Duplus, E; Williams, S C et al. (2001) Peroxisome proliferator-activated receptor gamma and chicken ovalbumin upstream promoter transcription factor II negatively regulate the phosphoenolpyruvate carboxykinase promoter via a common element. J Biol Chem 276:30561-9
Eubank, D W; Williams, S C; Beale, E G (2001) C/EBPbeta interacts with the P-enolpyruvate carboxykinase adipocyte-specific enhancer. Biochem Biophys Res Commun 285:811-9
Hsia, N; Cornwall, G A (2001) CCAAT/enhancer binding protein beta regulates expression of the cystatin-related epididymal spermatogenic (Cres) gene. Biol Reprod 65:1452-61

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