This is a competitive renewal of a Jointly Sponsored Neuroscience Training grant that funds prethesis Ph.D. students in the Neuroscience Training Program (NSP) at the University of Colorado Health Sciences Center (UCHSC). The NSP is an interdisciplinary Ph.D. granting Program started in 1986 that has been funded by NIH training grants since 1993. The 30 training faculty participating in this grant belong to six basic science and three clinical departments. The 30 faculty members have a combined funding of $13.9 M in direct annual grant dollars for an average of around $460,000 per year, and they have an outstanding record of previous training. The focus of the NSP is on training outstanding neuroscientists and academicians who will make significant contributions to neurobiology, become leaders in the field and impart these qualities to future generations of neuroscientists. In addition, we aim to foster development of students who approach research in a responsible, professional manner. In 2001 the Curriculum Committee, working in close collaboration with the new Director, Dr. Diego Restrepo, developed a new curriculum designed to attain these goals. We recruit highly qualified students on a national basis with undergraduate degrees in biology, chemistry, physical sciences or psychology. Among our current 21 students 38% are women, 10% are underrepresented minorities and 15% are from rural colleges and universities in the Rocky Mountain Region. Our graduates have a strong record as academicians and scientists;on the average they published 4 manuscripts during their tenure at UCHSC. We are requesting funds to support two students for two years each with a gradual increase throughout the period of funding to four students for two years each. The increase in the number of slots is based on the projected increase in Neuroscience faculty with the relocation of the entire School of Medicine to our new state-of-the-art Fitzsimons campus.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
5T32HD041697-09
Application #
7617847
Study Section
Special Emphasis Panel (ZDC1-SRB-W (41))
Program Officer
Henken, Deborah B
Project Start
2001-07-03
Project End
2011-04-30
Budget Start
2009-05-01
Budget End
2010-04-30
Support Year
9
Fiscal Year
2009
Total Cost
$176,267
Indirect Cost
Name
University of Colorado Denver
Department
Biology
Type
Schools of Medicine
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045
Frank, Guido K W; Shott, Megan E; DeGuzman, Marisa C et al. (2018) Dopamine D2 -141C Ins/Del and Taq1A polymorphisms, body mass index, and prediction error brain response. Transl Psychiatry 8:102
Sinnen, Brooke L; Bowen, Aaron B; Forte, Jeffrey S et al. (2017) Optogenetic Control of Synaptic Composition and Function. Neuron 93:646-660.e5
DeGuzman, Marisa; Shott, Megan E; Yang, Tony T et al. (2017) Association of Elevated Reward Prediction Error Response With Weight Gain in Adolescent Anorexia Nervosa. Am J Psychiatry 174:557-565
Goulding, Scott P; Szumlinski, Karen K; Contet, Candice et al. (2017) A mass spectrometry-based proteomic analysis of Homer2-interacting proteins in the mouse brain. J Proteomics 166:127-137
Lopert, Pamela; Patel, Manisha (2016) Mitochondrial mechanisms of redox cycling agents implicated in Parkinson's disease. J Neural Transm (Vienna) 123:113-23
Meredith, Frances L; Rennie, Katherine J (2016) Channeling your inner ear potassium: K(+) channels in vestibular hair cells. Hear Res 338:40-51
Hughes, Alexandria N; Hixon, Alison M; Josey, Megan (2016) A Schwanncentric View of Axon Arborization in Neuromuscular Junction (NMJ) Formation. J Neurosci 36:9760-2
Laumen, Geneviève; Ferber, Alexander T; Klump, Georg M et al. (2016) The Physiological Basis and Clinical Use of the Binaural Interaction Component of the Auditory Brainstem Response. Ear Hear 37:e276-e290
Ye, Wenlei; Chang, Rui B; Bushman, Jeremy D et al. (2016) The K+ channel KIR2.1 functions in tandem with proton influx to mediate sour taste transduction. Proc Natl Acad Sci U S A 113:E229-38
Jones, Heath G; Brown, Andrew D; Koka, Kanthaiah et al. (2015) Sound frequency-invariant neural coding of a frequency-dependent cue to sound source location. J Neurophysiol 114:531-9

Showing the most recent 10 out of 53 publications