The Interdisciplinary Training Program in Rehabilitation and Neuromuscular Plasticity (NMPT) at the University of Florida (UF) was initiated in 2003. The overall goal of this program is to help build a critical capacity of highly-trained rehabilitation scientists capable of conducting translational neuromuscular plasticity research. This predoctoral training program is unique in that it emphasizes the interaction and joint training of rehabilitation clinicians and basic science Trainees. The NMPT program draws students from five thriving PhD programs in the biomedical sciences, and our Faculty are active members of multiple Centers and Institutes devoted to distinct aspects of neuromuscular plasticity and rehabilitation. The program capitalizes on existing UF strengths including a core of well-established and highly productive rehabilitation investigators, outstanding research facilities, an exemplary record of collaboration, extraordinary institutional commitment, and a culture of successful mentorship in rehabilitation at multiple levels, including graduate students, postdoctoral fellows and junior faculty. Upon entering the program, each Trainee prepares an individualized training plan under the guidance of an experienced Faculty Mentor and Translational Research Co-Advisor. The individualized plan consists of a structured didactic program, specialized courses, journal clubs and seminars, laboratory research and multiple scientific dissemination experiences. The NMPT program is a well-defined, closely monitored program with clearly established training objectives and an effective evaluation process. We have a well- defined management structure that includes a Program Director, Curriculum Coordinator, a Translational Science Advisor, an Internal Steering Committee and an External Advisory Board. The NMPT program has been highly successful since its inception in 2003 with 25 of 29 graduates (86%) in academic or clinical research positions and 4 in industry research or government biomedical fields. Over the last cycle (2014- present), we graduated 10 NMPT Trainees. These Trainees have published an average of 12 PubMed- indexed manuscripts and all have obtained academic, research or biomedical positions. The NMPT program is achieving our goal of training scientists capable of engaging in translational rehabilitation research and sustaining independently funded research programs.

Public Health Relevance

Nationally, there is a shortage of rehabilitation scientists that are qualified to lead interdisciplinary research and develop innovative research programs that address the needs of individuals with disabilities. This proposal is a renewal application to continue training graduate students with either a clinical or basic science background to help fill this void. These students will perform research in a variety of neurological and neuromuscular conditions, across the lifespan.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Institutional National Research Service Award (T32)
Project #
2T32HD043730-16
Application #
9701758
Study Section
Special Emphasis Panel (ZHD1)
Program Officer
Nitkin, Ralph M
Project Start
2003-06-11
Project End
2024-04-30
Budget Start
2019-05-01
Budget End
2020-04-30
Support Year
16
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of Florida
Department
Other Health Professions
Type
Schools of Public Health
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Morton, Aaron B; Mor Huertas, Andres; Hinkley, J Matthew et al. (2018) Mitochondrial accumulation of doxorubicin in cardiac and diaphragm muscle following exercise preconditioning. Mitochondrion :
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Barnard, Alison M; Willcocks, Rebecca J; Finanger, Erika L et al. (2018) Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy. PLoS One 13:e0194283
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Streeter, Kristi A; Sunshine, Michael D; Patel, Shreya et al. (2017) Intermittent Hypoxia Enhances Functional Connectivity of Midcervical Spinal Interneurons. J Neurosci 37:8349-8362
Mercier, L M; Gonzalez-Rothi, E J; Streeter, K A et al. (2017) Intraspinal microstimulation and diaphragm activation after cervical spinal cord injury. J Neurophysiol 117:767-776
Nichols, Nicole L; Satriotomo, Irawan; Allen, Latoya L et al. (2017) Mechanisms of Enhanced Phrenic Long-Term Facilitation in SOD1G93A Rats. J Neurosci 37:5834-5845
Kavazis, Andreas N; Morton, Aaron B; Hall, Stephanie E et al. (2017) Effects of doxorubicin on cardiac muscle subsarcolemmal and intermyofibrillar mitochondria. Mitochondrion 34:9-19

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