7. Abstract We propose to continue the highly successful Stanford Genome Training Program for another five years, comprising the 23rd to the 27th year of the program. The SGTP has trained 178 Graduate Students and 65 Postdoctoral Fellows since its inception. Students will perform their research in the laboratories of an outstanding set of 64 participating faculty from fourteen departments in three Stanford schools; the majority of these investigators have previously trained students or postdocs supported by the SGTP. Collaborations and interactions among faculty and students are commonplace and facilitate student success and interdisciplinary research, and our well-resourced laboratories support the very best science. Trainees participate in extensive training programs that include, in addition to initial laboratory rotations and their subsequent thesis work, rigorous coursework, skill-building in computational and quantitative biology, and training in the responsible conduct of research, among other activities. The Stanford School of Medicine is highly supportive with programs that foster general skills, well-being and career advancement, and provides a highly advanced environment to conduct the most cutting-edge research. Our efforts to provide a diverse program have been extremely successful, with admitted diversity PhD candidates consistently making up between 10 and 20 percent of our Genetics Graduate Students and SGTP trainees. The productivity and publication record of the past trainees and the outcomes in terms of job placement has been exceptional, and we plan to continue to train the next generation of science leaders and highly skilled technical staff, both in academia and in the private sector.

Public Health Relevance

The Stanford Genome Training Program trains PhD students and Postdoctoral fellows to go on to productive technical and high-level leadership positions in the biomedical sciences, in academia and in the private sector. Specifically, we train the next generation of scientists in the field of genomics, which is becoming increasingly important in disease diagnosis and prevention due to tremendous technical advances and a confluence of computer science with biomedicine in the past decade. Many of those advances were catalyzed and driven by our former trainees and those of similar institutions.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Institutional National Research Service Award (T32)
Project #
2T32HG000044-21
Application #
9277796
Study Section
Special Emphasis Panel (ZHG1)
Program Officer
Colley, Heather
Project Start
1995-09-01
Project End
2022-08-31
Budget Start
2017-09-01
Budget End
2018-08-31
Support Year
21
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Stanford University
Department
Genetics
Type
Schools of Medicine
DUNS #
009214214
City
Stanford
State
CA
Country
United States
Zip Code
94304
Ofir, Gal; Melamed, Sarah; Sberro, Hila et al. (2018) DISARM is a widespread bacterial defence system with broad anti-phage activities. Nat Microbiol 3:90-98
Deng, Tanggang; Yan, Guobei; Song, Xin et al. (2018) Deubiquitylation and stabilization of p21 by USP11 is critical for cell-cycle progression and DNA damage responses. Proc Natl Acad Sci U S A 115:4678-4683
de la Fuente, Constanza; Ávila-Arcos, María C; Galimany, Jacqueline et al. (2018) Genomic insights into the origin and diversification of late maritime hunter-gatherers from the Chilean Patagonia. Proc Natl Acad Sci U S A 115:E4006-E4012
Karczewski, Konrad J; Snyder, Michael P (2018) Integrative omics for health and disease. Nat Rev Genet 19:299-310
Rappoport, Nadav; Toung, Jonathan; Hadley, Dexter et al. (2018) A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Sci Rep 8:226
Thompson, Abbey C; Capellini, Terence D; Guenther, Catherine A et al. (2018) A novel enhancer near the Pitx1 gene influences development and evolution of pelvic appendages in vertebrates. Elife 7:
Mezger, Anja; Klemm, Sandy; Mann, Ishminder et al. (2018) High-throughput chromatin accessibility profiling at single-cell resolution. Nat Commun 9:3647
Rong-Mullins, Xiaoqing; Ayers, Michael C; Summers, Mahmoud et al. (2018) Transcriptional Profiling of Saccharomyces cerevisiae Reveals the Impact of Variation of a Single Transcription Factor on Differential Gene Expression in 4NQO, Fermentable, and Nonfermentable Carbon Sources. G3 (Bethesda) 8:607-619
Bahrami-Nejad, Zahra; Zhao, Michael L; Tholen, Stefan et al. (2018) A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation. Cell Metab 27:854-868.e8
Zhou, Coral Y; Johnson, Stephanie L; Lee, Laura J et al. (2018) The Yeast INO80 Complex Operates as a Tunable DNA Length-Sensitive Switch to Regulate Nucleosome Sliding. Mol Cell 69:677-688.e9

Showing the most recent 10 out of 327 publications