The proposed training program will provide postdoctoral fellows with basic and clinical training in a collaborative multidisciplinary environment, which is essential for the development of advanced research skills and understanding of different mechanisms of cardiovascular disease, their translation into clinical research and new therapies that could target disease prevention and treatment. Currently, in its 40th year, this Boston University School of Medicine Multidisciplinary Training Program in Cardiovascular Research has offered qualified candidates holding an M.D. and/or Ph.D. degree, a 2-3 year long research and career training plan that allows them to succeed in pursuing scientific careers in cardiovascular sciences. The program focuses on the following Specific Aims: 1) Developing new investigators with the necessary competencies and breadth of expertise needed for the future of cardiovascular research; 2) Providing multidisciplinary training and exposure of trainees to advanced collaborative research; 3) Ensuring that trainees receive adequate mentorship in research and career development, and that mentorship is further advanced and evaluated; 4) Recruiting basic and clinical Fellows, retaining them in the scientific workforce and ensuring adequate representation of the nation's diversity in science; 5) Training of qualified scientists able to translate findings freely between the basic and clinical spheres, and to advance new cures for cardiovascular disease. The Multidisciplinary Training program will a) recruit qualified fellows with MD, or PhD degree from diverse backgrounds; b) provide a multidisciplinary training environment and unique research opportunities for basic and clinical fellows with a focus on interactive translational science, coupled with intensive mentorship and laboratory/research training in a particular investigational topic; c) teach trainees critical thining skills, how to ask relevant and feasible research questions, and develop effective written and oral communication skills; d) instill a sense of ethical behavior; e) involve minority and underrepresented scientists into advanced research, f) prepare trainees for research-intensive biomedical research careers, and provide the tools to achieve their career goals. In summary, the Boston University School of Medicine Multi-Disciplinary Cardiovascular Postdoctoral Training Program has a lengthy tradition of excellence in cardiovascular research, and will continue with its core goals of recruiting qualified MD and PhD candidates, commitment to diversity in its trainees including underrepresented minorities, providing outstanding mentorship, and producing experienced independent investigators in basic, translational and clinical cardiovascular science.

Public Health Relevance

For 39 years, the Multidisciplinary Postdoctoral Training Program in Cardiovascular Research has trained well-qualified individuals for full-time biomedical careers in the cardiovascular sciences. As cardiovascular disease continues to be the primary cause of death for Americans, training of a new generation of multidisciplinary researchers who will be able to successfully discover and translate basic science into clinical and pharmaceutical fields is crucial to improve public health.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007224-45
Application #
9993983
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Wang, Wayne C
Project Start
1976-07-01
Project End
2021-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
45
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Boston University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
604483045
City
Boston
State
MA
Country
United States
Zip Code
02118
Baveghems, Clive L; Anuganti, Murali; Pattammattel, Ajith et al. (2018) Tuning Enzyme/?-Zr(IV) Phosphate Nanoplate Interactions via Chemical Modification of Glucose Oxidase. Langmuir 34:480-491
Shim, Joon W; Madsen, Joseph R (2018) VEGF Signaling in Neurological Disorders. Int J Mol Sci 19:
Ray, Tathagat Dutta; Mekasha, Samrawit; Liang, Yanmei et al. (2018) Species-specific differences in regulation of macrophage inflammation by the C3a-C3a receptor axis. Innate Immun 24:66-78
Kolachalama, Vijaya B; Shashar, Moshe; Alousi, Faisal et al. (2018) Uremic Solute-Aryl Hydrocarbon Receptor-Tissue Factor Axis Associates with Thrombosis after Vascular Injury in Humans. J Am Soc Nephrol 29:1063-1072
Leiva, Orly; Leon, Catherine; Kah Ng, Seng et al. (2018) The role of extracellular matrix stiffness in megakaryocyte and platelet development and function. Am J Hematol 93:430-441
Shah, Ravi; Patel, Tushar; Freedman, Jane E (2018) Circulating Extracellular Vesicles in Human Disease. N Engl J Med 379:2180-2181
Taylor, Erik; Huang, Nasi; Bodde, Jacob et al. (2018) MRI of atherosclerosis and fatty liver disease in cholesterol fed rabbits. J Transl Med 16:215
Ko, Darae; Preis, Sarah R; Lubitz, Steven A et al. (2018) Relation of Orthostatic Hypotension With New-Onset Atrial Fibrillation (From the Framingham Heart Study). Am J Cardiol 121:596-601
Spartano, N L; Stevenson, M D; Xanthakis, V et al. (2017) Associations of objective physical activity with insulin sensitivity and circulating adipokine profile: the Framingham Heart Study. Clin Obes 7:59-69
Ko, Darae; Rahman, Faisal; Martins, Maria A P et al. (2017) Atrial fibrillation in women: treatment. Nat Rev Cardiol 14:113-124

Showing the most recent 10 out of 161 publications