EXCEED THE SPACE PROVIDED. The field of cardiovascular pathophysiology is undergoing rapid evolution with increasing emphasis on the genetics of cardiovascular disease. Human and murine studies have, for example, contributed to increased understanding of the role of growth factors and chronic inflammatory reactions in the evolution of vascular disease. To provide the next generation of investigators with the tools necessary to contribute to cardiovascular sciences, the University of Chicago's cardiovascular training program, now in it's 25th year, will focus its training programs on vascular disease and its genetic control as well as the role of the inflammatory response onvascular pathology. The Cardiovascular Pathophysiology and Biochemistry Training Program will provide pre- and post-doctoral leveltraining to scientists wishing to pursue research/academic careers in areas which represent the core of much of clinical vascular disease - lipids, genetics, risk factors, immune reactions, cell biology, vascular remodeling, acute vascular and myocardial injury and cell signaling. The Program draws its strength from faculty expertise in these areas and the program's current breadth has benefited from recent recruitment in areas such as structural biology, neurobiology, and genetics. Encouraging interdisciplinary research collaborations which bridge bench research and patient care, the program includes faculty drawn from the Departments of Organismal Biology and Anatomy, Molecular Genetics and Cell Biology, Biochemistry and Molecular Biology, Pharmacological Sciences and Neurobiology, Pathology, Medicine, Surgery, Pediatrics and Human Genetics, as well as the interdisciplinary, degree-granting committees of Human Nutrition and Nutritional Biology, Cell Physiology and Immunology. Trainees will share a common interest and expertise in cardiovascular sciences, but will have research and academic skills in a wide rage of fields necessary to address cardiovascular biology and disease. Students will be recruited through the Biomedical Sciences Cluster, one of four clusters under the newly reorganized Graduate Program in the Division of Biological Sciences which encourages interdisciplinary interactions among both trainees and faculty, and allows students flexibility in designing their course of study, provides for common course requirements and share seminar series. These are intended to foster and strengthen trainees' commitment to a scientific career as well as to build a vibrant cohort of pre- and post-doctoral trainees. The University has a long standing record of excellence in cardiovascular research and by capitalizing on the University's historical strength in translational, interdisciplinary research and our well-recognized teachers and scholars in the field, it is our goal to provide the next generation of investigators with the educational basis to define the specific genetic and environmental factors that contribute to cardiovascular disease. PERFORMANCE SITE ========================================Section End===========================================
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