The Hypertension Training Program at the University of California, San Diego is dedicated to the preparation of talented investigators in research fields which are pertinent to hypertension and the diseases associated with this common medical problem. The goal of this Hypertension Program is to train predoctoral and postdoctoral investigators for a research career and prepare them in a multidisciplinary and intregated fashion for a career in academic research. This is a competitive continuation application which brings together a variety of well funded and talented investigators utilizing a variety of disciplines in basic, translational and clinical research we propose to continue with four predoctoral and four postdoctoral trainees for a total of eight positions. All trainees receive an intensive experience in basic research coupled to participation in didactic courses and seminar series. Training is offered in multiple disciplines with eleven individual investigative groups. These groups have demonstrated significant collaboration in the past and have been funded by Program/Project and center grants relevant to hypertension research and a large General Clinical Research Center grant. Training is specifically offered in several disciplines including cell biology, molecular biology, immunology, genetics and genomics, biochemistry, and physiology. Predoctoral trainees are derived primarily from the highly successful Biomedical Sciences Graduate Program, Molecular Pathology Graduate Program and Medical Scientist Training Program at UCSD. Postdoctoral trainees are selected from an increasingly excellent pool of well-qualified applicants. Recruitment of new, experienced and well funded training program faculty have strengthened the program and increased the degree of investigator interaction and collaboration. Additional opportunities for multidisciplinary interactions and formalized mentoring programs have been added to the curriculum. Growth in research funding and major increases in laboratory research buildings on the UCSD campus also improve the likelihood of productivity within this research environment. Dr. Roland C. Blantz will continue as Program Director supported by Dr. Morton Printz, Co-Director.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
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Special Emphasis Panel (ZHL1-CSR-J (F1))
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Commarato, Michael
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University of California San Diego
Internal Medicine/Medicine
Schools of Medicine
La Jolla
United States
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Mongraw-Chaffin, Morgana; Allison, Matthew A; Burke, Gregory L et al. (2017) CT-Derived Body Fat Distribution and Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis. J Clin Endocrinol Metab 102:4173-4183
Mongraw-Chaffin, Morgana; Kanaya, Alka M; Kandula, Namratha R et al. (2017) The relationship between anthropometry and body composition from computed tomography: The Mediators of Atherosclerosis in South Asians Living in America Study. Ethn Health 22:565-574
Mongraw-Chaffin, Morgana; LaCroix, Andrea Z; Sears, Dorothy D et al. (2017) A prospective study of low fasting glucose with cardiovascular disease events and all-cause mortality: The Women's Health Initiative. Metabolism 70:116-124
Mongraw-Chaffin, Morgana; Foster, Meredith C; Kalyani, Rita R et al. (2016) Obesity Severity and Duration Are Associated With Incident Metabolic Syndrome: Evidence Against Metabolically Healthy Obesity From the Multi-Ethnic Study of Atherosclerosis. J Clin Endocrinol Metab 101:4117-4124
Elahimehr, Reza; Scheinok, Andrew T; McKay, Dianne B (2016) Hematopoietic stem cells and solid organ transplantation. Transplant Rev (Orlando) 30:227-34
Ratigan, Emmett D; McKay, Dianne B (2016) Exploring principles of hibernation for organ preservation. Transplant Rev (Orlando) 30:13-9
Beben, Tomasz; Ix, Joachim H; Shlipak, Michael G et al. (2016) Fibroblast Growth Factor-23 and Frailty in Elderly Community-Dwelling Individuals: The Cardiovascular Health Study. J Am Geriatr Soc 64:270-6
Nguyen, Hoang Anh; Rifkin, Dena E (2016) Cliff Dive or Slippery Slope: Trajectories of Kidney Function Decline and Implications for Survival After Hemodialysis Initiation. Am J Kidney Dis 68:173-175
Abdelmalek, Joseph A; Gansevoort, Ron T; Lambers Heerspink, Hiddo J et al. (2014) Estimated albumin excretion rate versus urine albumin-creatinine ratio for the assessment of albuminuria: a diagnostic test study from the Prevention of Renal and Vascular Endstage Disease (PREVEND) Study. Am J Kidney Dis 63:415-21
Blantz, Roland C (2014) Phenotypic characteristics of diabetic kidney involvement. Kidney Int 86:7-9

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