Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007591-07
Application #
2212564
Study Section
Research Training Review Committee (RTR)
Project Start
1985-07-01
Project End
1998-06-30
Budget Start
1994-07-01
Budget End
1995-06-30
Support Year
7
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Osterholt, Moritz; Sen, Shiraj; Dilsizian, Vasken et al. (2012) Targeted metabolic imaging to improve the management of heart disease. JACC Cardiovasc Imaging 5:214-26
Thakker, Geeta D; Frangogiannis, Nikolaos G; Zymek, Pawel T et al. (2008) Increased myocardial susceptibility to repetitive ischemia with high-fat diet-induced obesity. Obesity (Silver Spring) 16:2593-600
Essop, M Faadiel; Camp, Heidi S; Choi, Cheol Soo et al. (2008) Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice. Am J Physiol Heart Circ Physiol 295:H256-65
Sharma, Saumya; Guthrie, Patrick H; Chan, Suzanne S et al. (2007) Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart. Cardiovasc Res 76:71-80
Essop, M Faadiel; Chan, W Y A; Taegtmeyer, Heinrich (2007) Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress. FEBS J 274:5278-84
Sharma, Saumya; Ying, Jun; Razeghi, Peter et al. (2006) Atrophic remodeling of the transplanted rat heart. Cardiology 105:128-36
Sharma, Saumya; Dewald, Oliver; Adrogue, Julia et al. (2006) Induction of antioxidant gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species. Free Radic Biol Med 40:2223-31
Dewald, Oliver; Sharma, Saumya; Adrogue, Julia et al. (2005) Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity. Circulation 112:407-15
Golfman, Leonard S; Wilson, Christopher R; Sharma, Saumya et al. (2005) Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats. Am J Physiol Endocrinol Metab 289:E328-36
Adrogue, Julia V; Sharma, Saumya; Ngumbela, Kholiswa et al. (2005) Acclimatization to chronic hypobaric hypoxia is associated with a differential transcriptional profile between the right and left ventricle. Mol Cell Biochem 278:71-8

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