This program provides two years of basic science or outcomes research training in fields related to vascular surgery for developing academic clinicians and scientists. It addresses the critical need for adequate research training opportunities for vascular surgeons during their formative years. Research training in bioinformatics, molecular and cell biology, biomechanics, coagulation disorders, angiogenesis, and advanced outcomes research is provided with a focus on clinically relevant problems such as atherogenesis, intimal hyperplasia, prosthetic-host interactions, and pathologic thrombosis. Trainees pursue a program of intense investigation supplemented with course work in research design and statistics. The program is conducted and closely supervised by its directors, co-directors and mentors, all of whom have well-established records of peer- reviewed research, and who were selected both for their current research activities and their proven commitment to training research fellows. For each trainee, individual mentors are chosen from the program's faculty on the basis of their background and research interests. Trainees carry out their own projects under the close guidance of their mentor. Collaboration between laboratories and sharing of expertise is encouraged and fostered through multiple joint activities. Laboratory training can be supplemented by graduate level course work at Harvard Medical School?s Department of Health Care Policy and Research and with Harvard's Faculty of Arts and Sciences. Upon completion of the program, trainees are capable of independent research and possess the scientific and investigative background needed to obtain competitive peer-reviewed funding. In addition, graduates of the program have gained sufficient knowledge and skills necessary to provide translational expertise as they join medical school faculties. Selection of the eight trainees is based on their abilities in research and their desire to pursue an academic career that involves basic or clinical investigation. Applicants are resident physicians who have completed two to five years of post-graduate surgical training, or those who have a PhD with zero to five years of postdoctoral experience. Trainees are required to commit to two years of training. Only those applicants with clearly stated career goals of becoming surgeon-scientists or scientists, and with a keen interest in basic or outcomes research in fields related to vascular surgery are eligible. Candidates wishing to pursue this 2-year research fellowship during clinical training must provide evidence that they will be accepted back into their program upon completion.

Public Health Relevance

Vascular Surgeon-scientists guide research and provide practical ?hands on? perspectives on the biology of vascular diseases and the relevant problems and limitations of devices and interventions on blood vessels. This T32 program is designed to create a cadre of surgeon-scientists and scientists with expertise in research fundamentals essential to clinically driven, frontline ?bench-to-bedside to public policy? programs in treatment of vascular disease.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL007734-27
Application #
9894844
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Huang, Li-Shin
Project Start
1997-07-01
Project End
2024-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
27
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02215
Servais, Andrew B; Kienzle, Arne; Ysasi, Alexandra B et al. (2018) Structural heteropolysaccharides as air-tight sealants of the human pleura. J Biomed Mater Res B Appl Biomater :
Shean, Katie E; O'Donnell, Thomas F X; Deery, Sarah E et al. (2018) Regional variation in patient outcomes in carotid artery disease treatment in the Vascular Quality Initiative. J Vasc Surg 68:749-759
Kienzle, Arne; Servais, Andrew B; Ysasi, Alexandra B et al. (2018) Free-Floating Mesothelial Cells in Pleural Fluid After Lung Surgery. Front Med (Lausanne) 5:89
Baker, Meredith A; Mitchell, Paul D; O'Loughlin, Alison A et al. (2018) Characterization of Fatty Acid Profiles in Infants With Intestinal Failure-Associated Liver Disease. JPEN J Parenter Enteral Nutr 42:71-77
Deery, Sarah E; O'Donnell, Thomas F X; Zettervall, Sara L et al. (2018) Use of an Assistant Surgeon Does not Mitigate the Effect of Lead Surgeon Volume on Outcomes Following Open Repair of Intact Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg 55:714-719
Liang, Patric; Soden, Peter A; Zettervall, Sara L et al. (2018) Treatment outcomes in diabetic patients with chronic limb-threatening ischemia. J Vasc Surg 68:487-494
Shean, Katie E; Zettervall, Sara L; Deery, Sarah E et al. (2018) Fewer Complications in the Obese Following Lower Extremity Endovascular Interventions. Ann Vasc Surg 49:17-23
Buck, Dominique B; Soden, Peter A; Deery, Sarah E et al. (2018) Comparison of Endovascular Stent Grafts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries. Ann Vasc Surg 47:31-42
O'Donnell, Thomas F X; Schermerhorn, Marc L; Liang, Patric et al. (2018) Weekend Effect in Carotid Endarterectomy. Stroke 49:2945-2952
Baker, Meredith A; Nandivada, Prathima; Mitchell, Paul D et al. (2018) Pretreatment with intravenous fish oil reduces hepatic ischemia reperfusion injury in a murine model. Surgery 163:1035-1039

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