The Center for Clinical Epidemiology and Biostatistics (CCEB), together with the Cardiovascular Medicine Division and Pulmonary, Allergy, and Critical Care Division, both of the Department of Medicine, and the Division of Cardiology and Division of Pulmonary Medicine, both within the Department of Pediatrics, all of the Perelman School of Medicine at the University of Pennsylvania (Penn), propose to continue and enhance an innovative, rigorous, and successful two- to three-year research training program for clinicians in both adult and pediatric cardiology and pulmonary clinical research. The training program consists of required courses in epidemiology, clinical research methodology, biostatistics, and cardiopulmonary epidemiology;elective courses relevant to the trainees'methodologic interests;journal clubs and clinical research conferences conducted by participating faculty in the CCEB and adult and pediatric cardiology and pulmonary divisions;extensive independent readings;instruction in the responsible conduct of research;a professional development series;an apprenticeship experience with an experienced investigator;and the completion of an independent research project in cardiology or pulmonary clinical research. The program will: 1) train clinicians to be rigorous and independent academic investigators able to use the range of approaches available in epidemiology to address research issues in cardiovascular and pulmonary diseases related to the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care;2) provide closely mentored research experiences with faculty preceptors in clinical epidemiology and cardiovascular and pulmonary medicine;and 3) strengthen the links between traditional epidemiology and cardiovascular and pulmonary medicine. Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) program. Strengths of the proposed program are: 1) the long history of successful research and training programs in the CCEB and adult and pediatric cardiology and pulmonary divisions, including this training program;2) the collaborative links that have been forged among faculty with interests in clinical research in cardiovascular and pulmonary diseases;3) the comprehensive course offerings and research programs that are available to trainees;and 4) an extensive set of experienced and multidisciplinary faculty with successful training records. In addition, numerous existing large databases that can be used for research projects and training, a broad array of specialized analytic capabilities available for clinical studies employing methods of clinical epidemiology (e.g., clinical trials, case-control, cohort research, etc.), and commitmet of faculty to collaborative research and training, combine to provide an ideal environment for this training program. Finally, Penn and the Perelman School of Medicine promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for physicians.
There is a major national shortage of qualified clinician-scientists able to conduct the rigorous clinical research needed to address cardiovascular and pulmonary diseases. This training program addresses this shortage through the efforts of a distinguished, experienced, and committed training program faculty. Training will continue to be provided to those who desire careers as clinician-scientists focusing on cardiology and pulmonary clinical research through a program that provides trainees with the skills needed to design and conduct epidemiologic studies that will address the most vexing population-based questions in cardiovascular and pulmonary medicine.
|Palakshappa, Jessica A; Reilly, John P; Schweickert, William D et al. (2018) Quantitative peripheral muscle ultrasound in sepsis: Muscle area superior to thickness. J Crit Care 47:324-330|
|Hysinger, Erik B; Friedman, Nicholas L; Padula, Michael A et al. (2017) Tracheobronchomalacia Is Associated with Increased Morbidity in Bronchopulmonary Dysplasia. Ann Am Thorac Soc 14:|
|Porteous, Mary K; Lee, James C; Lederer, David J et al. (2017) Clinical Risk Factors and Prognostic Model for Primary Graft Dysfunction after Lung Transplantation in Patients with Pulmonary Hypertension. Ann Am Thorac Soc 14:1514-1522|
|Kohn, Rachel; Madden, Vanessa; Kahn, Jeremy M et al. (2017) Diffusion of Evidence-based Intensive Care Unit Organizational Practices. A State-Wide Analysis. Ann Am Thorac Soc 14:254-261|
|Jones, Tiffanie K; Meyer, Nuala J (2017) What's in a Number? Platelet Count Dynamics as a Novel Mediator of Acute Respiratory Distress Syndrome Survival. Am J Respir Crit Care Med 195:1285-1287|
|Porteous, Mary K; Rivera-Lebron, Belinda N; Kreider, Maryl et al. (2016) Determinants of 6-minute walk distance in patients with idiopathic pulmonary fibrosis undergoing lung transplant evaluation. Pulm Circ 6:30-6|
|Davis, Meghan F; Hu, Baofeng; Carroll, Karen C et al. (2016) Comparison of Culture-Based Methods for Identification of Colonization with Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus in the Context of Cocolonization. J Clin Microbiol 54:1907-1911|
|Bakhru, Rita N; McWilliams, David J; Wiebe, Douglas J et al. (2016) Intensive Care Unit Structure Variation and Implications for Early Mobilization Practices. An International Survey. Ann Am Thorac Soc 13:1527-37|
|Perman, Sarah M; Stanton, Emily; Soar, Jasmeet et al. (2016) Location of In-Hospital Cardiac Arrest in the United States-Variability in Event Rate and Outcomes. J Am Heart Assoc 5:|
|Kohn, Rachel; Halpern, Scott D; Kerlin, Meeta Prasad (2016) The implications of intensive care unit capacity strain for the care of critically ill patients. Rev Bras Ter Intensiva 28:366-368|
Showing the most recent 10 out of 79 publications