The primary goal of our training program in Cardiovascular Biomechanics and Imaging is to attract, train, and graduate highly qualified, multi-disciplinary scientists in the area of cardiovascular bioengineering at pre- and post-doctoral levels. The program was created 10 years ago in response to: 1) the dearth of training opportunities available at the intersection between cardiovascular medicine and bioengineering at the University of Colorado and indeed within the Greater Rocky Mountain region; and 2) the strong institutional commitment to build bioengineering research and training within the University of Colorado. We believe the first 10 years have produced outstanding outcomes, with all pre-doctoral and post-doctoral graduates of the program in research positions within academia or industry, and many successfully receiving research grants and trainees of their own. Further, NHLBI T32 funding has been extraordinarily important in leveraging a large amount of additional funding from the University of Colorado, which bodes well for our next cycle of trainees. We believe the combination of outstanding outcomes, significant and continuing institutional support and growing reputation make a compelling argument to continue this program for the next 5 years, and thereby establish the University of Colorado as a premiere training destination for cardiovascular bioengineering.

Public Health Relevance

This program aims to train the next generation of scientists to perform research and training at the interface between cardiovascular medicine and bioengineering. The program aims to provide trainees with sound engineering breadth and depth, as well as a robust understanding of clinical and biomedical research and vocabulary in the cardiovascular sciences.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZHL1-CSR-F (O1))
Program Officer
Huang, Li-Shin
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Colorado Denver
Biomedical Engineering
Schools of Medicine
United States
Zip Code
Schäfer, Michal; Kheyfets, Vitaly O; Barker, Alex J et al. (2018) Reduced shear stress and associated aortic deformation in the thoracic aorta of patients with chronic obstructive pulmonary disease. J Vasc Surg 68:246-253
Gates, Phillip E; Gurung, Arati; Mazzaro, Luciano et al. (2018) Measurement of Wall Shear Stress Exerted by Flowing Blood in the Human Carotid Artery: Ultrasound Doppler Velocimetry and Echo Particle Image Velocimetry. Ultrasound Med Biol 44:1392-1401
St Clair, Joshua R; Ramirez, David; Passman, Samantha et al. (2018) Contrast-enhanced ultrasound measurement of pancreatic blood flow dynamics predicts type 1 diabetes progression in preclinical models. Nat Commun 9:1742
Govindarajan, Tina; Shandas, Robin (2017) Shape Memory Polymers Containing Higher Acrylate Content Display Increased Endothelial Cell Attachment. Polymers (Basel) 9:
McClatchey, Penn M; Frisbee, Jefferson C; Reusch, Jane E B (2017) A conceptual framework for predicting and addressing the consequences of disease-related microvascular dysfunction. Microcirculation 24:
Gurung, Arati; Gates, Phillip E; Mazzaro, Luciano et al. (2017) Echo Particle Image Velocimetry for Estimation of Carotid Artery Wall Shear Stress: Repeatability, Reproducibility and Comparison with Phase-Contrast Magnetic Resonance Imaging. Ultrasound Med Biol 43:1618-1627
Mason McClatchey, P; Bauer, Timothy A; Regensteiner, Judith G et al. (2017) Dissociation of local and global skeletal muscle oxygen transport metrics in type 2 diabetes. J Diabetes Complications 31:1311-1317
Mason McClatchey, P; Wu, Fan; Olfert, I Mark et al. (2017) Impaired Tissue Oxygenation in Metabolic Syndrome Requires Increased Microvascular Perfusion Heterogeneity. J Cardiovasc Transl Res 10:69-81
McClatchey, P Mason; Keller, Amy C; Bouchard, Ron et al. (2016) Fully automated software for quantitative measurements of mitochondrial morphology. Mitochondrion 26:58-71
McClatchey, P Mason; Keller, Amy C; Bouchard, Ron et al. (2016) Raw and processed microscope images of fixed cells at baseline and following various experimental perturbations. Data Brief 6:998-1006

Showing the most recent 10 out of 61 publications