This a competitive renewal T32 application for a training grant in cardiovascular epidemiology with a special focus on genetic and molecular epidemiology. The program is designed for M.D. investigators who are transitioning from clinical training in General Internal Medicine to subspecialty training in cardiovascular medicine. Key features of the program include completion of a Master's degree in Clinical and Population Translation Science with supplemental training in genetic, genomics and proteomics. The applicants will also attend the 10-day seminar in Cardiovascular Epidemiology and the Genetic Approaches to Complex Heart, Lung, and Blood diseases seminar, participate in a laboratory practicum exposing them to some of the latest technologies available in genomics and proteomics, and receive additional training in the responsible conduct of research and project management. The goal of this training program is to train clinical cardiovascular investigators who are well equipped to apply the new advances in genetic, genomics, and proteomics to the conduct of cardiovascular epidemiological research and to assist in the translation of new basic science advances to the clinical arena.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
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NHLBI Institutional Training Mechanism Review Committee (NITM)
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Silsbee, Lorraine M
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Wake Forest University Health Sciences
Internal Medicine/Medicine
Schools of Medicine
United States
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Aladin, Amer I; Al Rifai, Mahmoud; Rasool, Shereen H et al. (2018) Relation of Coronary Artery Calcium and Extra-Coronary Aortic Calcium to Incident Hypertension (from the Multi-Ethnic Study of Atherosclerosis). Am J Cardiol 121:210-216
Leigh, Adam; McEvoy, John W; Garg, Parveen et al. (2018) Coronary Artery Calcium Scores and Atherosclerotic Cardiovascular Disease Risk Stratification in Smokers: MESA. JACC Cardiovasc Imaging :
Leigh, J Adam; Kaplan, Robert C; Swett, Katrina et al. (2017) Smoking intensity and duration is associated with cardiac structure and function: the ECHOcardiographic Study of Hispanics/Latinos. Open Heart 4:e000614
Oseni, Abdullahi O; Qureshi, Waqas T; Almahmoud, Mohamed F et al. (2017) Left ventricular hypertrophy by ECG versus cardiac MRI as a predictor for heart failure. Heart 103:49-54
Pflum, Adam; Gomadam, Pallavi; Mehta, Hardik et al. (2017) Effect of Chronic Kidney Disease and Supplemental Polyunsaturated Fatty Acid Use on Exercise Levels During Cardiac Rehabilitation in Patients With Coronary Artery Disease. J Cardiopulm Rehabil Prev 37:199-206
Alhalabi, Lubna; Singleton, Matthew J; Oseni, Abdullahi O et al. (2017) Relation of Higher Resting Heart Rate to Risk of Cardiovascular Versus Noncardiovascular Death. Am J Cardiol 119:1003-1007
Leigh, J Adam; O'Neal, Wesley T; Soliman, Elsayed Z (2016) Electrocardiographic Left Ventricular Hypertrophy as a Predictor of Cardiovascular Disease Independent of Left Ventricular Anatomy in Subjects Aged ?65 Years. Am J Cardiol 117:1831-5
Leigh, J Adam; Alvarez, Manrique; Rodriguez, Carlos J (2016) Ethnic Minorities and Coronary Heart Disease: an Update and Future Directions. Curr Atheroscler Rep 18:9
Hartman, Lauren; Barnes, Erin; Bachmann, Laura et al. (2016) Opiate Injection-associated Infective Endocarditis in the Southeastern United States. Am J Med Sci 352:603-608
Chew, Merwyn; Xie, Jing; Klein, Ronald et al. (2016) Sleep apnea and retinal signs in cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis. Sleep Breath 20:15-23

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