The diagnosis and management of CV disease relies on non-invasive testing to enhance the identification of high risk patients and optimize management strategies. Molecular imaging is a key tool to improve risk assessment and lead to more individualized approaches to diagnosing and treating disease. Our objective is to produce CV imaging specialists with the clinical and investigative skills to establish independent careers, mentor others, and lead their own CV Imaging programs. We designed a comprehensive curriculum-based training program in multi-modality CV Imaging research that includes: (1) a 2-year training program in translational research taught by a multidisciplinary faculty of MD and/or PhD scientists;(2) an extended didactic clinical and basic science research curriculum consisting of orientation lectures;basic analytic and bioethics courses, advanced course work (including two program-specific advanced courses);and ongoing learning opportunities;and (3) a mentored clinical or translational research experience that includes formal training in research methodology, and the development of a research project including protocol development, experimental execution, critical data analysis, oral presentation, manuscript writing, and grant preparation. We seek NIH support for research training in imaging science for 2 fellows (MD or MD PhD) annually. Our program is opened to cardiologists, radiologists and other imaging specialists. We have assembled a group of 12 outstanding faculty mentors, each of whom are pursuing research at the cutting-edge of cardiac imaging science. Collectively, they have over 50 active extramural grants and have mentored over 170 pre/post doctoral fellows in various aspects of basic and clinical cardiac imaging research. Extensive collaboration among the faculty, trainees, and other investigators throughout the BWH, MGH, and Harvard Medical School communities, further increase the Program's scientific impact. We anticipate that our trainees will fulfill our overall objectives and that our graduates will disseminate CV Imaging training, ultimately creating a critical mass of imaging scientists to meet the health care needs of our population.

Public Health Relevance

There is a severe shortage of trained individuals with the knowledge and skills to bridge the gap between imaging technology and the evidence to support the use of such technology. The proposed training program is particularly valuable now that cardiovascular imaging has become the 'hot button'for policy makers because of its effect on costs.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
5T32HL094301-04
Application #
8488465
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Wang, Wayne C
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
4
Fiscal Year
2013
Total Cost
$315,018
Indirect Cost
$20,298
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Gupta, Ankur; Harrington, Meagan; Albert, Christine M et al. (2018) Myocardial Scar But Not Ischemia Is Associated With Defibrillator Shocks and Sudden Cardiac Death in Stable Patients With Reduced Left Ventricular Ejection Fraction. JACC Clin Electrophysiol 4:1200-1210
Gupta, Ankur; Yancy, Clyde W; Fonarow, Gregg C (2018) Evaluating Readmission-Need for More Clarity on Methods-Reply. JAMA Cardiol 3:265-266
Gupta, Ankur; Bajaj, Navkaranbir S; Arora, Pankaj et al. (2018) FFR-guided multivessel stenting reduces urgent revascularization compared with infarct-related artery only stenting in ST-elevation myocardial infarction: A meta-analysis of randomized controlled trials. Int J Cardiol 252:63-67
Venkatraman, A; Hardas, S; Patel, N et al. (2018) Galectin-3: an emerging biomarker in stroke and cerebrovascular diseases. Eur J Neurol 25:238-246
Shinde, Arti V; Su, Ya; Palanski, Brad A et al. (2018) Pharmacologic inhibition of the enzymatic effects of tissue transglutaminase reduces cardiac fibrosis and attenuates cardiomyocyte hypertrophy following pressure overload. J Mol Cell Cardiol 117:36-48
Vaduganathan, Muthiah; Qamar, Arman; Gupta, Ankur et al. (2018) Patent Foramen Ovale Closure for Secondary Prevention of Cryptogenic Stroke: Updated Meta-Analysis of Randomized Clinical Trials. Am J Med 131:575-577
Wu, Candace; Singh, Avinainder; Collins, Bradley et al. (2018) Causes of Troponin Elevation and Associated Mortality in Young Patients. Am J Med 131:284-292.e1
Kalra, Rajat; Arora, Garima; Patel, Nirav et al. (2018) Targeted Temperature Management After Cardiac Arrest: Systematic Review and Meta-analyses. Anesth Analg 126:867-875
Fujikura, Kana; Peltzer, Bradley; Tiwari, Nidhish et al. (2018) Reduced global longitudinal strain is associated with increased risk of cardiovascular events or death after kidney transplant. Int J Cardiol 272:323-328
Singh, Avinainder; Collins, Bradley L; Gupta, Ankur et al. (2018) Cardiovascular Risk and Statin Eligibility of Young Adults After an MI: Partners YOUNG-MI Registry. J Am Coll Cardiol 71:292-302

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