This T32 Vascular Surgery Education and Research Training (VascTrain) Program is designed to train vascular surgery residents in the fundamentals of basic and clinical cardiovascular research. This will be accomplished using a training committee comprised of a principal trainer and a team of associate trainers in a closely supervised training program. The training scheme is based on interactions between the training committee and the trainee in the form of weekly training research sessions. The VascTrain Program is integrated into a Vascular Surgery residency program where all residents participate in a 2 year curriculum designed to provide research training. Funding for 3 positions is sought to support trainees who will enter the program after 3 years of vascular surgery or surgery residency. A few PhD post-doctoral fellows will be accepted into this program. The research areas of focus are based on cardiovascular diseases, its consequences and its treatments. General areas of investigation include the pathogenesis and treatment of intimal hyperplasia, tissue engineered autologous conduits, tissue ischemia induced angiogenesis and wound healing, computational analysis of aortic aneurysm progress and rupture, cardiovascular imaging, epidemiology of cardiovascular disease, and pharmacotherapeutics. The program introduces a multidisciplinary approach to vascular biology research and a dedicated approach to clinical/translational research.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Institutional National Research Service Award (T32)
Project #
1T32HL098036-01A1
Application #
7941369
Study Section
NHLBI Institutional Training Mechanism Review Committee (NITM)
Program Officer
Commarato, Michael
Project Start
2010-07-01
Project End
2015-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
1
Fiscal Year
2010
Total Cost
$187,015
Indirect Cost
Name
University of Pittsburgh
Department
Surgery
Type
Schools of Medicine
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Haskett, Darren G; Saleh, Kamiel S; Lorentz, Katherine L et al. (2018) An exploratory study on the preparation and evaluation of a ""same-day"" adipose stem cell-based tissue-engineered vascular graft. J Thorac Cardiovasc Surg 156:1814-1822.e3
Xu, Jun; Cui, Xiangdong; Li, Jiehua et al. (2018) Chloroquine improves the response to ischemic muscle injury and increases HMGB1 after arterial ligation. J Vasc Surg 67:910-921
Sridharan, Natalie D; Chaer, Rabih A; Wu, Bryan Boyuan et al. (2018) An Accumulated Deficits Model Predicts Perioperative and Long-term Adverse Events after Carotid Endarterectomy. Ann Vasc Surg 46:97-103
Domenick Sridharan, Natalie; Thirumala, Partha; Chaer, Rabih et al. (2018) Predictors of cross-clamp-induced intraoperative monitoring changes during carotid endarterectomy using both electroencephalography and somatosensory evoked potentials. J Vasc Surg 67:191-198
Sridharan, Natalie D; Boitet, Aureline; Smith, Kenneth et al. (2018) Cost-effectiveness analysis of drug-coated therapies in the superficial femoral artery. J Vasc Surg 67:343-352
Mohapatra, Abhisekh; Lowenkamp, Mikayla N; Henry, Jon C et al. (2018) Prior Endovascular Intervention Is Not Detrimental to Pedal Bypasses for Ischemic Wounds. Ann Vasc Surg 50:80-87
Mohapatra, Abhisekh; Henry, Jon C; Avgerinos, Efthimios D et al. (2018) Bypass versus endovascular intervention for healing ischemic foot wounds secondary to tibial arterial disease. J Vasc Surg 68:168-175
Liang, Nathan L; Reitz, Katherine M; Makaroun, Michel S et al. (2018) Comparable perioperative mortality outcomes in younger patients undergoing elective open and endovascular abdominal aortic aneurysm repair. J Vasc Surg 67:1404-1409.e2
Mohapatra, Abhisekh; Salem, Karim M; Jaman, Emade et al. (2018) Risk factors for perioperative mortality after revascularization for acute aortic occlusion. J Vasc Surg 68:1789-1795
Mohapatra, Abhisekh; Henry, Jon C; Avgerinos, Efthimios D et al. (2018) Heel Wounds Predict Mortality but Not Amputation after Infrapopliteal Revascularization. Ann Vasc Surg 51:78-85

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