As imaging technology and molecular medicine advances, more complex questions arise often requiring the convergence of perspectives from multiple disciplines. The future of cardiovascular imaging will most likely be practiced by integrated multidisciplinary teams with diverse expertise. The goal of this research training program is to provide multi-disciplinary post-doctoral multi-modality training in molecular and translational cardiovascular imaging for highly qualified fellows holding either a MD or/and PhD, in preparation for academic careers as independent investigators in the highly clinically relevant field of cardiovascular imaging. Applications will be encouraged from both clinical and basic science departments, with particular attention to the recruitment of minority, disabled, and disadvantaged candidates. We anticipate enrollment of 4 post-doctoral applicants each year into the programs, with an equal balance between physicians and scientists. Post-doctoral fellowship training will be 2-3 years in duration. There will be three primary research focuses in the post-doctoral training, 1) cardiovascular molecular imaging, 2) cardiovascular imaging technologies and analyses, and 3) translational cardiovascular imaging. The primary faculty for this program are from the Yale School of Engineering and Applied Sciences and from multiple departments within the Yale School of Medicine, including: Internal Medicine (Section of Cardiovascular Medicine), Diagnostic Radiology, Surgery, Anesthesiology, and Therapeutic Radiology. The sponsoring faculty was selected based on extramural support, research productivity, and commitment to multi-disciplinary training. Trainee progress will be monitored by individual mentors, the trainee's advisory committee, and the Program Directors. Drs. Sinusas and Duncan will co-manage the program to assure a balance and integration of the training of applicants in the relevant clinical and engineering sciences.

National Institute of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Institutional National Research Service Award (T32)
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NHLBI Institutional Training Mechanism Review Committee (NITM)
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Carlson, Drew E
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Yale University
Internal Medicine/Medicine
Schools of Medicine
New Haven
United States
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Mohy-Ud-Din, Hassan; Boutagy, Nabil E; Stendahl, John C et al. (2018) Quantification of intramyocardial blood volume with 99mTc-RBC SPECT-CT imaging: A preclinical study. J Nucl Cardiol 25:2096-2111
Feher, Attila; Srivastava, Ajay; Quail, Michael A et al. (2018) Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients. JACC Cardiovasc Imaging :
Boutagy, Nabil E; Wu, Jing; Cai, Zhengxi et al. (2018) In Vivo Reactive Oxygen Species Detection With a Novel Positron Emission Tomography Tracer, 18F-DHMT, Allows for Early Detection of Anthracycline-Induced Cardiotoxicity in Rodents. JACC Basic Transl Sci 3:378-390
Guerriero, Kathryn A; Wilson, Steven R; Boutagy, Nabil E et al. (2018) Cutaneous Toxicity in a Laboratory Beagle (Canis lupus familiaris) after Chronic Administration of Doxorubicin Hydrochloride. Comp Med 68:56-62
Boutagy, Nabil E; Sinusas, Albert J (2017) Imaging of the Cardiac Sympathetic Nervous System Has Potential Value in the Evaluation of Patients with Heart Failure with Preserved Ejection Fraction. J Nucl Med 58:781-783
Maxfield, Mark W; Stacy, Mitchel R; Kurobe, Hirotsugu et al. (2017) Novel application and serial evaluation of tissue-engineered portal vein grafts in a murine model. Regen Med 12:929-938
Feher, Attila; Sinusas, Albert J (2017) Assessment of right ventricular metabolism: An emerging tool for monitoring pulmonary artery hypertension. J Nucl Cardiol 24:1990-1993
Liu, Qingyi; Mohy-Ud-Din, Hassan; Boutagy, Nabil E et al. (2017) Fully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT. Phys Med Biol 62:3944-3957
Ferrandino, Giuseppe; Kaspari, Rachel R; Reyna-Neyra, Andrea et al. (2017) An extremely high dietary iodide supply forestalls severe hypothyroidism in Na+/I- symporter (NIS) knockout mice. Sci Rep 7:5329
Boutagy, Nabil E; Sinusas, Albert J (2017) Recent Advances and Clinical Applications of PET Cardiac Autonomic Nervous System Imaging. Curr Cardiol Rep 19:33

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