The Clinical Research Training Program (CRTP), now in its twenty-eighth year, offers intensive, interdisciplinary postdoctoral training in clinical research to outstanding psychiatrists (MDs) and biological and behavioral scientists (PhDs). Our primary objective is trainees developing a sophisticated understanding of the research tools relevant to clinical research in psychiatry and in behavioral sciences. Trainees study experimental design, contemporary statistics, relevant assessments, and computer processing approaches in order to implement their own research. The multidisciplinary nature of the program (e.g. developmental psychology, neurophysiology) emphasizes varied perspectives in designing, conducting, and interpreting research findings. The CRTP is oriented towards developing clinical investigators who will in two-years be ready to conduct their own independent clinical research, or join already established clinical research teams as junior colleagues. Specific components of the CRTP are: 1) placement of each Fellow in a funded clinical research training site;2) a weekly interdisciplinary research training seminar. Led by the training Directors, and attended by Fellows, visiting faculty, and other outstanding researchers in the area;3) attendance at relevant courses within the Harvard University complex and other Boston universities and hospitals. The multiple research areas included in the program build upon the research resources present within the Department of psychiatry at Harvard, and include 42 research training sites. We have added 12 new training sites. 5 female and two minority (African American) training faculty. Core aspects of training are through the weekly seminar and Fellows'ongoing work with their research preceptor. A new aspect of the CRTP is our four-point strategic plan to enhance the number of under-represented minority trainees. This plan will include a newly-formed Diversity Advisory Board, and strong alliances with other organizations (e.g., APA) with ongoing Minority Fellowship and related programs. Trainees have continued to obtain full-time and tenured positions at major universities, have shown a strong publication record, and received over 100 research grants, including 17 NIH/NIMH Career Development Awards. We believe that the strength of our program will continue, and that the field of psychiatry will greatly benefit from this rigorous, multidisciplinary training of a new generation of clinical research investigators.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Institutional National Research Service Award (T32)
Project #
Application #
Study Section
Special Emphasis Panel (ZMH1-ERB-Z (02))
Program Officer
Wynne, Debra K
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Judge Baker Children's Center
United States
Zip Code
Higger, Matt; Shenton, Martha; Bouix, Sylvain (2018) Pairwise, Ordinal Outlier Detection of Traumatic Brain Injuries. Brainlesion (2017) 10670:100-110
Chouinard, Virginie-Anne; Henderson, David C; Dalla Man, Chiara et al. (2018) Impaired insulin signaling in unaffected siblings and patients with first-episode psychosis. Mol Psychiatry :
Hamoda, Hesham M; Makhlouf, A T; Fitzsimmons, J et al. (2018) Abnormalities in thalamo-cortical connections in patients with first-episode schizophrenia: a two-tensor tractography study. Brain Imaging Behav :
McCarthy-Jones, Simon; Oestreich, Lena K L; Lyall, Amanda E et al. (2018) Childhood adversity associated with white matter alteration in the corpus callosum, corona radiata, and uncinate fasciculus of psychiatrically healthy adults. Brain Imaging Behav 12:449-458
Lyall, A E; Pasternak, O; Robinson, D G et al. (2018) Greater extracellular free-water in first-episode psychosis predicts better neurocognitive functioning. Mol Psychiatry 23:701-707
Seitz, Johanna; Rathi, Yogesh; Lyall, Amanda et al. (2018) Alteration of gray matter microstructure in schizophrenia. Brain Imaging Behav 12:54-63
Nevarez, Michael D; Morrill, Melinda I; Waldinger, Robert J (2018) Thriving in midlife: The roles of childhood nurturance and adult defense mechanisms. J Res Pers 74:35-41
Aguilar, David D; Giuffrida, Andrea; Lodge, Daniel J (2018) Adolescent Synthetic Cannabinoid Exposure Produces Enduring Changes in Dopamine Neuron Activity in a Rodent Model of Schizophrenia Susceptibility. Int J Neuropsychopharmacol 21:393-403
Dogan, Asli Ercan; Yuksel, Cagri; Du, Fei et al. (2018) Brain lactate and pH in schizophrenia and bipolar disorder: a systematic review of findings from magnetic resonance studies. Neuropsychopharmacology 43:1681-1690
Allen, Patricia J; Jimerson, David C; Kanarek, Robin B et al. (2017) Impaired reversal learning in an animal model of anorexia nervosa. Physiol Behav 179:313-318

Showing the most recent 10 out of 143 publications