This submission is a competing continuation of our on-going """"""""Neuropsychology of HIV/AIDS Fellowship"""""""" at UCLA that, for the past 10 years, has provided training support for postdoctoral Fellows specializing in HIV research. We propose to continue training three post-doctoral Fellows per year with each Fellow receiving two years of funding. Emphasis will be on training Fellows in clinical research in the Neuropsychology of HIV/AIDS. Fellows will be engaged in a primary research project and one or more secondary research projects, working with Dr. Paul Satz (P.I.), Dr. Charles Hinkin (Co-PI), and Dr. Eric Miller (Co-PI), as well as, with other primary faculty. This HIV research Fellowship is embedded in the UCLA Neuropsychology Postdoctoral Training Program in Neuropsychology, headed by Dr. Satz since 1981, that annually trains 8-10 fellows in clinical and research Neuropsychology. The HIV training faculty, hold multiple NIH and private research grants, thus affording Fellows the opportunity to participate on a wide-array of research projects. Fellows also have the opportunity to collaborate with multiple supervisors, exposing them to a breadth of experience and supervisory styles. Fellows will also encounter a heavy clinical exposure to HIV-1 infected individuals and will provide clinical neuropsychological assessments on at least one HIV-1 infected patient per week. Additional clinical experience will be available at community-based AIDS service organization (AIDS Project Los Angeles). A rich didactic base, including coursework from 8-5 every Thursday, rounds out the training experience. We are committed to continue recruitment and training of women and members of traditionally underrepresented groups in our Fellowship, who together represented 64 percent of the Fellows supported by this training grant. Over the past ten years we successfully recruited and trained 8 Fellows who were members of underrepresented groups (40 percent of our total Fellows enrolled). The successful career trajectories of our graduated? Fellows demonstrates the success of our program. We are eager to continue our training efforts in this important area of clinical research of another five years.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Institutional National Research Service Award (T32)
Project #
5T32MH019535-13
Application #
6750129
Study Section
Special Emphasis Panel (ZMH1-BRB-S (03))
Program Officer
Stoff, David M
Project Start
1991-04-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
13
Fiscal Year
2004
Total Cost
$141,227
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Jones, Jacob D; Kuhn, Taylor; Mahmood, Zanjbeel et al. (2018) Longitudinal intra-individual variability in neuropsychological performance relates to white matter changes in HIV. Neuropsychology 32:206-212
Kuhn, Taylor; Kaufmann, Tobias; Doan, Nhat Trung et al. (2018) An augmented aging process in brain white matter in HIV. Hum Brain Mapp 39:2532-2540
Anderson, Ariana E; Jones, Jacob D; Thaler, Nicholas S et al. (2018) Intraindividual variability in neuropsychological performance predicts cognitive decline and death in HIV. Neuropsychology 32:966-972
Jones, Jacob D; Kuhn, Taylor P; Szymkowicz, Sarah M (2018) Reverters from PD-MCI to cognitively intact are at risk for future cognitive impairment: Analysis of the PPMI cohort. Parkinsonism Relat Disord 47:3-7
Thames, April D; Kuhn, Taylor P; Mahmood, Zanjbeel et al. (2018) Effects of social adversity and HIV on subcortical shape and neurocognitive function. Brain Imaging Behav 12:96-108
Szymkowicz, Sarah M; Dotson, Vonetta M; Jones, Jacob D et al. (2018) Symptom Dimensions of Depression and Apathy and Their Relationship With Cognition in Parkinson's Disease. J Int Neuropsychol Soc 24:269-282
Thames, April D; Kuhn, Taylor P; Williamson, Timothy J et al. (2017) Marijuana effects on changes in brain structure and cognitive function among HIV+ and HIV- adults. Drug Alcohol Depend 170:120-127
Kuhn, Taylor; Schonfeld, Daniel; Sayegh, Philip et al. (2017) The effects of HIV and aging on subcortical shape alterations: A 3D morphometric study. Hum Brain Mapp 38:1025-1037
Kuhn, Taylor; Sayegh, Philip; Jones, Jacob D et al. (2017) Improvements in brain and behavior following eradication of hepatitis C. J Neurovirol 23:593-602
Sayegh, Philip; Thaler, Nicholas S; Arentoft, Alyssa et al. (2016) Medication Adherence in HIV-Positive African Americans: The Roles of Age, Health Beliefs, and Sensation Seeking. Cogent Psychol 3:

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