This program has the purpose of preparing postdoctoral students for careers in biomedical research and teaching. Fields of specialization are developmental neurobiology, integrative neurophysiology and small systems analysis, systems neuroscience, biophysics, molecular neurobiology, neurogenetics, neuroanatomy and neurochemistry. The form of the training further illustrates the interdisciplinary nature of the program. Primary emphasis is given to research undertaken through cooperation of several neurobiology laboratories, each with its own specific approach. Training takes place in the Division of Biological Sciences of UCSD which fosters a spirit of interdisciplinary fusion motivated by the founders of the campus, in which many different types of biology are being pursued and many different approaches to solving problems are being shared. All participants have access to the wider neurobiological community, including the faculty and equipment at institutions affiliated with UCSD: The Neuroscience Department of UCSD's School of Medicine, the Howard Hughes Medical Institute, the Scripps Institution of Oceanography, the Salk Institute, the Scripps Research Foundation and the Neurosciences Institute. These resources have proved to be valuable components of the training environment. Seminars include weekly journal clubs, weekly talks from local and visiting neurobiologists, and specialized courses on a wide range of topics. These complement the research program, which is conducted under the sponsorship of individual faculty members. Postdoctoral trainees also participate in the teaching done by faculty, by lecturing in specialized neurobiology courses. However emphasis is placed on developing the potential of individual trainees for independent and original research. The four postdoctoral trainees are typically Ph.D.s, usually from other neurobiology programs, although they occasionally come from other areas of science. The selection criteria are superior scholarship in rigorous undergraduate and graduate programs, solid evidence of excellent and original research abilities, recommendations from past advisors, and expressions of commitment to careers in biomedical research. Effort is made to identify individuals of minority status. Research training takes place chiefly in the laboratories of the participating faculty, although the close ties with other laboratories and institutes and the interdisciplinary spirit of the community make it likely that some parts of a trainee's research will take place in other local laboratories.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
3T32NS007220-30S1
Application #
8329043
Study Section
NST-2 Subcommittee (NST)
Program Officer
Korn, Stephen J
Project Start
1982-07-01
Project End
2012-06-30
Budget Start
2011-07-01
Budget End
2012-06-30
Support Year
30
Fiscal Year
2011
Total Cost
$52,810
Indirect Cost
Name
University of California San Diego
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Thakar, Sonal; Wang, Liqing; Yu, Ting et al. (2017) Evidence for opposing roles of Celsr3 and Vangl2 in glutamatergic synapse formation. Proc Natl Acad Sci U S A 114:E610-E618
McCulloch, Katherine A; Qi, Yingchuan B; Takayanagi-Kiya, Seika et al. (2017) Novel Mutations in Synaptic Transmission Genes Suppress Neuronal Hyperexcitation in Caenorhabditis elegans. G3 (Bethesda) 7:2055-2063
Rodrigues, Elizabeth M; Scudder, Samantha L; Goo, Marisa S et al. (2016) A?-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1. J Neurosci 36:1590-5
Cherra 3rd, Salvatore J; Jin, Yishi (2016) A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density. Neuron 89:325-36
Makino, Hiroshi; Hwang, Eun Jung; Hedrick, Nathan G et al. (2016) Circuit Mechanisms of Sensorimotor Learning. Neuron 92:705-721
Cherra 3rd, Salvatore J; Jin, Yishi (2015) Advances in synapse formation: forging connections in the worm. Wiley Interdiscip Rev Dev Biol 4:85-97
Piscopo, Denise M; El-Danaf, Rana N; Huberman, Andrew D et al. (2013) Diverse visual features encoded in mouse lateral geniculate nucleus. J Neurosci 33:4642-56
Choi, Charles; Nitabach, Michael N (2013) Membrane-tethered ligands: tools for cell-autonomous pharmacological manipulation of biological circuits. Physiology (Bethesda) 28:164-71
Onishi, Keisuke; Shafer, Beth; Lo, Charles et al. (2013) Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance. J Neurosci 33:19071-85
Grossman, Emily N; Giurumescu, Claudiu A; Chisholm, Andrew D (2013) Mechanisms of ephrin receptor protein kinase-independent signaling in amphid axon guidance in Caenorhabditis elegans. Genetics 195:899-913

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