This is a proposal to continue a long-standing postdoctoral training program at Brandeis University. This program is designed to enhance the quantitative skills of a diverse group of investigators involved in solving the problems posed by myriad disorders of the nervous system. To understand neurological disorders and develop new therapies a cadre of outstanding investigators with strong quantitative skills working in research intensive academic institutions, in industry, and in other capacities, is required. Trainees with PhDs in mathematics, physics, engineering, and computer science will be brought into neuroscience through a program of mentored laboratory research and course work. Trainees with PhDs in the biological sciences will enter a program of mentored laboratory research and receive additional training in applying quantitative methods to understand basic and translational work in neuroscience. All trainees will take courses, participate in seminars, journal clubs, and will obtain mentoring experience and training in the responsible conduct of science. Trainees will also development a working relationship with an External Mentor who will provide additional training perspectives to the trainees and to the Program. Efforts to increase the diversity of the scientific work force are described.

Public Health Relevance

Brain disorders are responsible for significant pain and suffering and economic cost. To facilitate the understanding of brain function and the development of new therapies for brain disorders, this program will produce a generation of quantitatively strong brain scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS007292-33
Application #
9515068
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Weigand, Letitia Alexis
Project Start
1986-07-01
Project End
2021-06-30
Budget Start
2018-07-01
Budget End
2019-06-30
Support Year
33
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Brandeis University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
616845814
City
Waltham
State
MA
Country
United States
Zip Code
Goodwin, Patricia R; Meng, Alice; Moore, Jessie et al. (2018) MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila. Cell Rep 23:3776-3786
Amichetti, Nicole M; Atagi, Eriko; Kong, Ying-Yee et al. (2018) Linguistic Context Versus Semantic Competition in Word Recognition by Younger and Older Adults With Cochlear Implants. Ear Hear 39:101-109
Zhou, Jie; Du, Xuewen; Berciu, Cristina et al. (2018) Cellular Uptake of A Taurine-Modified, Ester Bond-Decorated D-Peptide Derivative via Dynamin-Based Endocytosis and Macropinocytosis. Mol Ther 26:648-658
Rogers, Chad S; Payne, Lisa; Maharjan, Sujala et al. (2018) Older adults show impaired modulation of attentional alpha oscillations: Evidence from dichotic listening. Psychol Aging 33:246-258
Otopalik, Adriane G; Sutton, Alexander C; Banghart, Matthew et al. (2017) When complex neuronal structures may not matter. Elife 6:
Abraira, Victoria E; Kuehn, Emily D; Chirila, Anda M et al. (2017) The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell 168:295-310.e19
Kenny, Katelyn; Royer, Leandro; Moore, Anna R et al. (2017) Rem2 signaling affects neuronal structure and function in part by regulation of gene expression. Mol Cell Neurosci 85:190-201
Del Signore, Steven J; Biber, Sarah A; Lehmann, Katherine S et al. (2017) dOCRL maintains immune cell quiescence by regulating endosomal traffic. PLoS Genet 13:e1007052
Otopalik, Adriane G; Goeritz, Marie L; Sutton, Alexander C et al. (2017) Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion. Elife 6:
Atagi, Eriko; Bent, Tessa (2017) Nonnative Accent Discrimination with Words and Sentences. Phonetica 74:173-191

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