This competitive renewal application requests 5 additional years support for 5 post-doctoral trainees in cerebrovascular disease (stroke) to complete a 2 year fellowship. The program's mission is to develop neurologists to become clinician-scientists in cerebrovascular disease. Stroke is the number one cause of adult disability;effective treatments are urgently needed.
The specific aims of the training program are to: (1) provide opportunities for the study of clinical research in stroke;(2) provide trainin in laboratory investigation of cerebrovascular disease. The last 5 years of funding under the T32 Training Grant has resulted in significant growth in our stroke program on many fronts. Continued funding for another 5 years would therefore allow us to: 1) provide uninterrupted growth of our research mentoring program for stroke fellows;2) train ethnically diverse researchers and physician-scientists who will make an impact on treating cerebrovascular disease. Our overall goal is to help accomplish improved care of stroke patients by mentoring clinician-scientists who will dedicate their careers to investigating the pathophysiology and epidemiology of cerebrovascular disease and the application of this knowledge to new therapeutic advances. Faculty mentors have been carefully selected to provide a multidisciplinary training experience in cerebrovascular disease. Potential trainees must have completed a neurology residency and demonstrate a commitment to a career carrying out research in cerebrovascular disease.

Public Health Relevance

The goal of our training program is to improve the care of stroke patients by mentoring and developing clinician-scientists in the field of cerebrovascular disease. We seek continued funding for our training program which enables our trainees to conduct high quality laboratory and clinical research in stroke and provides them critical support to launch their careers in academic medicine.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
2T32NS007412-16
Application #
8666610
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Korn, Stephen J
Project Start
1998-07-06
Project End
2019-06-30
Budget Start
2014-07-01
Budget End
2015-06-30
Support Year
16
Fiscal Year
2014
Total Cost
Indirect Cost
Name
University of Texas Health Science Center Houston
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Houston
State
TX
Country
United States
Zip Code
77225
Sarraj, Amrou; Hassan, Ameer; Savitz, Sean I et al. (2018) Endovascular Thrombectomy for Mild Strokes: How Low Should We Go? Stroke 49:2398-2405
Berekashvili, Ketevan; Soomro, Jazba; Shen, Loren et al. (2018) Safety and Feasibility of Argatroban, Recombinant Tissue Plasminogen Activator, and Intra-Arterial Therapy in Stroke (ARTSS-IA Study). J Stroke Cerebrovasc Dis 27:3647-3651
Zha, Alicia; Vahidy, Farhaan; Randhawa, Jaskaren et al. (2018) Association Between Splenic Contraction and the Systemic Inflammatory Response After Acute Ischemic Stroke Varies with Age and Race. Transl Stroke Res 9:484-492
Barreto, Andrew D; Ford, Gary A; Shen, Loren et al. (2017) Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke). Stroke 48:1608-1616
Vahidy, Farhaan; Nguyen, Claude; Albright, Karen C et al. (2016) Transferring Patients with Intracerebral Hemorrhage Does Not Increase In-Hospital Mortality. PLoS One 11:e0159174
Karamchandani, Rahul R; Vahidy, Farhaan; Bajgur, Suhas et al. (2015) Early depression screening is feasible in hospitalized stroke patients. PLoS One 10:e0128246
Nguyen, Claude; Mir, Osman; Vahidy, Farhaan et al. (2015) Resource Utilization for Patients with Intracerebral Hemorrhage Transferred to a Comprehensive Stroke Center. J Stroke Cerebrovasc Dis 24:2866-74
Elliott, Andrea; Wetzel, Jeremy; Roper, Tiffany et al. (2015) Thromboelastography in patients with acute ischemic stroke. Int J Stroke 10:194-201
Kawano-Castillo, Jorge; Ward, Eric; Elliott, Andrea et al. (2014) Thrombelastography detects possible coagulation disturbance in patients with intracerebral hemorrhage with hematoma enlargement. Stroke 45:683-8
Acosta, Indrani; Bloch, Sivan; Morales, Miriam et al. (2014) Predicting the need for hospital admission of TIA patients. J Neurol Sci 336:83-6

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