The Neurobiology Curriculum (NBIO) at UNC-Chapel Hill (UNC-CH) is one of the oldest neuroscience graduate training programs in the US having granted PhDs continuously for 47 years. NBIO has a reputation for excellence and rigor, and there has been constant recruitment of new faculty which keeps the program innovative. In support of NBIO, we request renewed funding for T32 NS007431, Neuroscience Predoctoral Training at UNC-Chapel Hill. This T32 supports 10 stipends and travel funds for NBIO students in the 1st and 2nd years of training. The Training Grant importantly impacts neuroscience graduate training at UNC-Chapel Hill (UNC-CH) in several ways: 1) T32 support for travel provides access to career-enhancing enrichment activities for the most promising students. 2) T32 support increases student access to the best training labs. 3) T32 support enhances our recruitment and mentoring of URM trainees. 4) T32 support leverages resources provided by the UNC School of Medicine and thereby helps support the seminar series and the annual UNC Neuroscience Symposium. NBIO is a comprehensive neuroscience graduate training program that has strong leadership and standing committees to guide the program, a thoughtfully constructed and rigorous Core course, and a diverse group of electives. There are numerous, well-attended community activities including weekly seminars, a weekly data presentation series for the students, an annual symposium, presentation of the internationally recognized Perl/UNC Neuroscience Prize, and an annual student research day. Mentoring in the program is continuous and there are well-designed activities to educate students about academic and non-academic careers. Faculty and students have outstanding publication records. Multiple trainees (27%) received individual NRSAs during the reporting period. Almost all trainees who received PhDs during the past 10 years are pursuing scientific careers including academic positions, positions in pharma/biotech, other scientific careers, completion of MD/PhD training, and postdoctoral fellowships. There is an outstanding record of recruiting and retaining URM trainees. Renewal would allow UNC-CH to continue training the next generation of neuroscientists including a strong contingent from URM groups.

Public Health Relevance

'Neuroscience Predoctoral Training at UNC-Chapel Hill' supports predoctoral trainees in the Neurobiology Curriculum (NBIO) at the University of North Carolina -Chapel Hill. Trainees take a rigorous course work and perform research in diverse areas of neuroscience with an emphasis on diseases-related approaches. Almost all trainees from the past ten years are pursuing careers in science with many associated with academic medical centers.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS007431-17
Application #
8847806
Study Section
Special Emphasis Panel (ZAG1)
Program Officer
Korn, Stephen J
Project Start
1997-09-30
Project End
2019-06-30
Budget Start
2015-07-01
Budget End
2016-06-30
Support Year
17
Fiscal Year
2015
Total Cost
Indirect Cost
Name
University of North Carolina Chapel Hill
Department
Neurology
Type
Schools of Medicine
DUNS #
608195277
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599
Catavero, Christina; Bao, Hechen; Song, Juan (2018) Neural mechanisms underlying GABAergic regulation of adult hippocampal neurogenesis. Cell Tissue Res 371:33-46
Jha, Shaili C; Xia, Kai; Schmitt, James Eric et al. (2018) Genetic influences on neonatal cortical thickness and surface area. Hum Brain Mapp 39:4998-5013
Makhijani, Viren H; Van Voorhies, Kalynn; Besheer, Joyce (2018) The mineralocorticoid receptor antagonist spironolactone reduces alcohol self-administration in female and male rats. Pharmacol Biochem Behav 175:10-18
Andersen, Elizabeth H; Lewis, Gregory F; Belger, Aysenil (2018) Aberrant parasympathetic reactivity to acute psychosocial stress in male patients with schizophrenia spectrum disorders. Psychiatry Res 265:39-47
Carlson, Alexander L; Xia, Kai; Azcarate-Peril, M Andrea et al. (2018) Infant Gut Microbiome Associated With Cognitive Development. Biol Psychiatry 83:148-159
Townsend, Leah B; Smith, Spencer L (2017) Genotype- and sex-dependent effects of altered Cntnap2 expression on the function of visual cortical areas. J Neurodev Disord 9:2
McHenry, Jenna A; Otis, James M; Rossi, Mark A et al. (2017) Hormonal gain control of a medial preoptic area social reward circuit. Nat Neurosci 20:449-458
Xia, K; Zhang, J; Ahn, M et al. (2017) Genome-wide association analysis identifies common variants influencing infant brain volumes. Transl Psychiatry 7:e1188
Otis, James M; Namboodiri, Vijay M K; Matan, Ana M et al. (2017) Prefrontal cortex output circuits guide reward seeking through divergent cue encoding. Nature 543:103-107
Stringfield, S J; Higginbotham, J A; Wang, R et al. (2017) Role of glucocorticoid receptor-mediated mechanisms in cocaine memory enhancement. Neuropharmacology 123:349-358

Showing the most recent 10 out of 51 publications