The Interdisciplinary Program in Neurosciences (IPN) at Georgetown University is a broad-based, trans-disciplinary, non-departmental graduate program leading to a Ph.D. in Neuroscience. The program, established in 1994, aims to train students in the scholarly pursuit of research in integrative neuroscience, from the level of the cell to that of the intact behaving organism. The 32 core training faculty and 9 supporting faculty are drawn from 13 clinical and basic science departments on the Main Campus and Medical Center. They span a breadth of inquiry, ranging from neurotransmitter receptors and signal transduction, to behavior and human cognition. Areas of research strengths include 1) neural injury, cell death, and plasticity in the CNS; 2) regulation of neurotrophic factors and their receptors; 3) synaptic modulation by liquid-gated and voltage-gated channels, 4) brain-behavior regulation of endocrine, immune and autonomic function; and 5) telencephalic neural networks subserving sensory processing, memory and language. The Training Grant funds will support the first 2 years of predoctoral training (4/year); thereafter support comes from the thesis laboratory or individual fellowships. Aggressive recruitment of trainees from underrepresented racial and ethnic groups is a top priority of the Georgetown IPN. The training environment is ideal for collaborative, pandisciplinary research efforts of both faculty and trainees. Over 40% of the training faculty have their laboratories in close proximity in the New Research Building (opened in 1994), with state-of-the-art core facilities and custom designed laboratory and office space. Most faculty have previous and ongoing collaborations; students are encouraged to seek co-mentorship between faculty with overlapping interests and complementary approaches. All training faculty have research grant support and fully equipped facilities for training pre- and post-doctoral students. The Georgetown Institute for Cognitive and Computational Sciences, located in the New Research Building, has expanded the resources available to the neuroscience training program, in terms of equipment, facilities and faculty expertise. Other noteworthy facilities include the Research Resources Facility, a fully accredited, centralized animal facility housing a wide variety of mammalian animal species, and the Medical Center Library, one of the most advanced in the nation. The training program includes broad-based didactic coursework, as well as rotations in laboratories of the training faculty. The trainees participate in a seminar series, national professional meetings, journal clubs, intensive laboratory research, and training in several essential professional skills (writing and reviewing manuscripts, grantmanship, mentorship, teaching, conflict resolution, career choices, oral presentations) and their ethical dimensions. Opportunities for gaining practical teaching experience at the undergraduate and secondary school levels are abundant and encouraged.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
5T32NS041231-05
Application #
6934551
Study Section
NST-2 Subcommittee (NST)
Program Officer
Korn, Stephen J
Project Start
2001-07-15
Project End
2006-06-30
Budget Start
2005-07-01
Budget End
2006-06-30
Support Year
5
Fiscal Year
2005
Total Cost
$335,139
Indirect Cost
Name
Georgetown University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057
Speidell, Andrew P; Demby, Tamar; Lee, Yichien et al. (2018) Development of a Human APOE Knock-in Mouse Model for Study of Cognitive Function After Cancer Chemotherapy. Neurotox Res :
Sun, Zhi Yong; Bozzelli, P Lorenzo; Caccavano, Adam et al. (2018) Disruption of perineuronal nets increases the frequency of sharp wave ripple events. Hippocampus 28:42-52
Elorette, Catherine; Forcelli, Patrick A; Saunders, Richard C et al. (2018) Colocalization of Tectal Inputs With Amygdala-Projecting Neurons in the Macaque Pulvinar. Front Neural Circuits 12:91
Aguilar, Brittany L; Forcelli, Patrick A; Malkova, Ludise (2018) Inhibition of the substantia nigra pars reticulata produces divergent effects on sensorimotor gating in rats and monkeys. Sci Rep 8:9369
Breeden, A L; Siegle, G J; Norr, M E et al. (2017) Coupling between spontaneous pupillary fluctuations and brain activity relates to inattentiveness. Eur J Neurosci 45:260-266
Conant, Katherine; Daniele, Stefano; Bozzelli, P Lorenzo et al. (2017) Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation. J Neuroinflammation 14:56
Erickson, Laura C; Rauschecker, Josef P; Turkeltaub, Peter E (2017) Meta-analytic connectivity modeling of the human superior temporal sulcus. Brain Struct Funct 222:267-285
Forcelli, Patrick A; DesJardin, Jacqueline T; West, Elizabeth A et al. (2016) Amygdala selectively modulates defensive responses evoked from the superior colliculus in non-human primates. Soc Cogn Affect Neurosci 11:2009-2019
Vitantonio, Daniel; Xu, Weifeng; Geng, Xinling et al. (2015) Emergence of dominant initiation sites for interictal spikes in rat neocortex. J Neurophysiol 114:3315-25
Harrington, Rachael M; Chan, Evan; Turkeltaub, Peter E et al. (2015) Simple Partial Status Epilepticus One-day Post Single-pulse TMS to the Affected Hemisphere in a Participant With Chronic Stroke. Brain Stimul 8:682-3

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