The Neurosciences Graduate Program (NGP) at UC San Diego (UCSD) is committed to training the next generation of neuroscience leaders. The NGP brings together world-class research institutions and laboratories at UCSD, The Salk Institute, The Scripps Research Institute, and the Sanford Burnham Institute, to create one of the largest and most diverse neuroscience environments in the world. The proposed training program combines this environment with a progressive, quantitatively rigorous curriculum covering multiple neuroscience disciplines, mentored research with world-leading investigators, collaborative opportunities across clinical and academic settings, and mentored professional development. Research productivity and placement of prior NGP trainees is outstanding, with most trainees continuing in scientific research and higher education. The NGP consistently ranks among the top graduate programs in US. The proposed training program supports 1st and 2nd-year NGP students and is endorsed by strong institutional support. The program reinforces close, productive interactions between students and faculty. Incoming students receive intensive hands-on laboratory training in a two-week Boot Camp that provides a unique bonding experience. Students choose thesis labs after completing the core courses and research lab rotations in the first year. Student progress is closely monitored through formal evaluations, with individually tailored career advising and mentorship. Scientific interactions among students and faculty are facilitated through student-run journal clubs, discussion courses, student talks, colloquia, outreach programs, recruitment activities, and an annual retreat. The NGP has met prior goals to increase program size by enhancing institutional support, and to strengthen recruitment and retention of underrepresented students. Representation of URM students in the NGP is now the highest among all UCSD STEM graduate programs, and the overall size of the program has increased by nearly 40%, to 102 PhD students, since 2012, while recruitment and admission have remained highly competitive (applications have doubled since 2007). Our guiding mission to develop tomorrow's leading neuroscientists is founded on rigorous skills in experimental design, statistical methodology and quantitative reasoning. Over the next five years, the NGP has set a goal to strengthen and comprehensively integrate the tenets of quantitative rigor, reproducibility, and research transparency into all aspects of the training program. This includes broadening the quantitative scope of the NGP by expanding the successful Computational Neuroscience specialization, modifying curricula, and altering mentoring practices to anticipate future challenges for data collection, access, and analysis. Our goal is a broad interdisciplinary neuroscience training environment that emphasizes strong quantitative skills coupled to rigorous experimental design and statistical methodology.

Public Health Relevance

The UCSD Neurosciences Graduate Training Program combines rigorous, quantitative training across the full spectrum of neuroscience sub-disciplines with a proven ability to prepare next generation science leaders, through mentored research in world-leading laboratories and comprehensive professional development.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Institutional National Research Service Award (T32)
Project #
2T32NS061847-11A1
Application #
9935939
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Korn, Stephen J
Project Start
2008-07-01
Project End
2025-06-30
Budget Start
2020-07-15
Budget End
2021-06-30
Support Year
11
Fiscal Year
2020
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Sancho, Laura; Bloodgood, Brenda L (2018) Functional Distinctions between Spine and Dendritic Synapses Made onto Parvalbumin-Positive Interneurons in Mouse Cortex. Cell Rep 24:2075-2087
Kato, Hiroyuki K; Asinof, Samuel K; Isaacson, Jeffry S (2017) Network-Level Control of Frequency Tuning in Auditory Cortex. Neuron 95:412-423.e4
Fife, Kathryn H; Gutierrez-Reed, Navarre A; Zell, Vivien et al. (2017) Causal role for the subthalamic nucleus in interrupting behavior. Elife 6:
Hwang, Eun Jung; Dahlen, Jeffrey E; Mukundan, Madan et al. (2017) History-based action selection bias in posterior parietal cortex. Nat Commun 8:1242
Poo, Mu-Ming; Pignatelli, Michele; Ryan, Tomás J et al. (2016) What is memory? The present state of the engram. BMC Biol 14:40
Rodrigues, Elizabeth M; Scudder, Samantha L; Goo, Marisa S et al. (2016) A?-Induced Synaptic Alterations Require the E3 Ubiquitin Ligase Nedd4-1. J Neurosci 36:1590-5
Hazen, Jennifer L; Faust, Gregory G; Rodriguez, Alberto R et al. (2016) The Complete Genome Sequences, Unique Mutational Spectra, and Developmental Potency of Adult Neurons Revealed by Cloning. Neuron 89:1223-1236
Yoo, Ji Hoon; Zell, Vivien; Gutierrez-Reed, Navarre et al. (2016) Ventral tegmental area glutamate neurons co-release GABA and promote positive reinforcement. Nat Commun 7:13697
Sapiurka, Maya; Squire, Larry R; Clark, Robert E (2016) Distinct roles of hippocampus and medial prefrontal cortex in spatial and nonspatial memory. Hippocampus 26:1515-1524
Somkuwar, Sucharita S; Fannon-Pavlich, McKenzie J; Ghofranian, Atoosa et al. (2016) Wheel running reduces ethanol seeking by increasing neuronal activation and reducing oligodendroglial/neuroinflammatory factors in the medial prefrontal cortex. Brain Behav Immun 58:357-368

Showing the most recent 10 out of 38 publications