The long-term objective of this program is to train lab animal medicine veterinarians to be competitive research scientists.
The specific aims are to 1) select individuals completing an internship or residency in lab animal medicine, 2) matriculate trainees in a rigid discipline oriented Ph.D. program, 3) emphasize a laboratory based research project on lab animal diseases or animal models of human disease under the mentorship of an NIH RO-1 funded faculty scientist, and 4) conceptualize, conduct, analyze and publish research results required for the Ph.D. thesis. Upon completion of the program, trainees will be prepared to function as independent experimental research lab animal specialists. The foundation of the program is through interaction between the academic disciplines of clinical medicine, pathology, clinical pathology, endocrinology, microbiology, nutrition, immunology and epidemiology on one hand, with service disciplines of lab animal and primate medicine. UC Davis has a rich research environment in the California Regional Primate Research Center, Animal Resources Service, Centers for Comparative Medicine and for Vector-borne Diseases and departments within the Schools of Veterinary medicine and Medicine. The program format is based upon individually tailored Ph.D. programs in comparative pathology, physiology, nutrition, microbiology, epidemiology, or immunology. The first 12 to 18 months of the three year program will be spent primarily in taking advanced course work appropriate to lab animal medicine an the discipline selected for thesis research. The major thrust of the program is a thesis research project on a lab animal problem or model of human disease. Candidates with the DVM and previous lab animal training will be selected by an advisory committee on the basis of academic performance, demonstrated interest and motivation toward an academic research career. Four stipends are required for each of the years of the program. The goals of the proposed program are in keeping with the School of Veterinary Medicine's commitment to train athe next generation of research scientists interested in bettering animal and human health.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Institutional National Research Service Award (T32)
Project #
5T32RR007038-12
Application #
6017398
Study Section
Special Emphasis Panel (CM)
Program Officer
Whitehair, Leo A
Project Start
1988-07-01
Project End
2001-06-30
Budget Start
1999-07-01
Budget End
2000-06-30
Support Year
12
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of California Davis
Department
Type
Schools of Veterinary Medicine
DUNS #
094878337
City
Davis
State
CA
Country
United States
Zip Code
95618
Carlson-Bremer, Daphne; Colegrove, Kathleen M; Gulland, Frances M D et al. (2015) Epidemiology and pathology of Toxoplasma gondii in free-ranging California sea lions (Zalophus californianus). J Wildl Dis 51:362-73
Luff, Jennifer A; Yuan, Hang; Kennedy, Douglas et al. (2014) Keratinocyte antiviral response to Poly(dA:dT) stimulation and papillomavirus infection in a canine model of X-linked severe combined immunodeficiency. PLoS One 9:e102033
Lokken, Kristen L; Mooney, Jason P; Butler, Brian P et al. (2014) Malaria parasite infection compromises control of concurrent systemic non-typhoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function. PLoS Pathog 10:e1004049
Mooney, J P; Butler, B P; Lokken, K L et al. (2014) The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection. Mucosal Immunol 7:1302-11
Luff, Jennifer A; Yuan, Hang; Suter, Maja M et al. (2013) Canine keratinocytes upregulate type I interferons and proinflammatory cytokines in response to poly(dA:dT) but not to canine papillomavirus. Vet Immunol Immunopathol 153:177-86
Fritz, Heather M; Buchholz, Kerry R; Chen, Xiucui et al. (2012) Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One 7:e29998
Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew et al. (2012) Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One 7:e29955
Kelly, Kristi R; Kapatkin, Amy R; Zwingenberger, Allison L et al. (2012) Efficacy of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with osteomyelitis. Comp Med 62:311-5
Fritz, H; Barr, B; Packham, A et al. (2012) Methods to produce and safely work with large numbers of Toxoplasma gondii oocysts and bradyzoite cysts. J Microbiol Methods 88:47-52
Carlson-Bremer, Daphne; Johnson, Christine K; Miller, Robin H et al. (2012) Identification of two novel coccidian species shed by California sea lions (Zalophus californianus). J Parasitol 98:347-54

Showing the most recent 10 out of 43 publications