This Comparative Medical Science Training Program seeks to provide graduate Ph.D. training for talented veterinarians to become effective scientists in biomedical research while developing an appreciation for the broad context of Comparative Medicine. The foundation of the training program is the University of California Center for Comparative Medicine, a research and teaching center that is co-sponsored by the Schools of Veterinary Medicine and Medicine. The Center for Comparative Medicine provides a unique training environment that exists nowhere else in the world. Six training positions are requested for this funding period. Trainees will be selected based upon academic excellence and demonstrated interest/experience in research careers. Depending upon career interest of the candidate, each trainee will be matched with relevant mentors who maintain robust, well-funded research programs. Training will emphasize rigorous scientific research, scientific writing, verbal communication, and interaction with a community of M.D., D.V.M and Ph.D. scientists and allied professionals that profess the concept of Comparative Medicine.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Institutional National Research Service Award (T32)
Project #
5T32RR007038-16
Application #
6639852
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Program Officer
Grieder, Franziska B
Project Start
1988-07-01
Project End
2006-06-30
Budget Start
2003-07-01
Budget End
2004-06-30
Support Year
16
Fiscal Year
2003
Total Cost
$278,935
Indirect Cost
Name
University of California Davis
Department
Veterinary Sciences
Type
Schools of Veterinary Medicine
DUNS #
047120084
City
Davis
State
CA
Country
United States
Zip Code
95618
Carlson-Bremer, Daphne; Colegrove, Kathleen M; Gulland, Frances M D et al. (2015) Epidemiology and pathology of Toxoplasma gondii in free-ranging California sea lions (Zalophus californianus). J Wildl Dis 51:362-73
Luff, Jennifer A; Yuan, Hang; Kennedy, Douglas et al. (2014) Keratinocyte antiviral response to Poly(dA:dT) stimulation and papillomavirus infection in a canine model of X-linked severe combined immunodeficiency. PLoS One 9:e102033
Lokken, Kristen L; Mooney, Jason P; Butler, Brian P et al. (2014) Malaria parasite infection compromises control of concurrent systemic non-typhoidal Salmonella infection via IL-10-mediated alteration of myeloid cell function. PLoS Pathog 10:e1004049
Mooney, J P; Butler, B P; Lokken, K L et al. (2014) The mucosal inflammatory response to non-typhoidal Salmonella in the intestine is blunted by IL-10 during concurrent malaria parasite infection. Mucosal Immunol 7:1302-11
Luff, Jennifer A; Yuan, Hang; Suter, Maja M et al. (2013) Canine keratinocytes upregulate type I interferons and proinflammatory cytokines in response to poly(dA:dT) but not to canine papillomavirus. Vet Immunol Immunopathol 153:177-86
Fritz, Heather M; Buchholz, Kerry R; Chen, Xiucui et al. (2012) Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PLoS One 7:e29998
Fritz, Heather M; Bowyer, Paul W; Bogyo, Matthew et al. (2012) Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. PLoS One 7:e29955
Kelly, Kristi R; Kapatkin, Amy R; Zwingenberger, Allison L et al. (2012) Efficacy of antibiotic-impregnated polymethylmethacrylate beads in a rhesus macaque (Macaca mulatta) with osteomyelitis. Comp Med 62:311-5
Fritz, H; Barr, B; Packham, A et al. (2012) Methods to produce and safely work with large numbers of Toxoplasma gondii oocysts and bradyzoite cysts. J Microbiol Methods 88:47-52
Carlson-Bremer, Daphne; Johnson, Christine K; Miller, Robin H et al. (2012) Identification of two novel coccidian species shed by California sea lions (Zalophus californianus). J Parasitol 98:347-54

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