Abstract

(3) The Statistics Core, led by Drs. Conti, Stram, Azen, and Thomas, will characterize haplotypes, perform association analyses, and comprehensively evaluate the impact of numerous genetic polymorphisms and pharmacological interventions via a biologically motivated Bayesian hierarchical model.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DA020830-05
Application #
7878103
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
5
Fiscal Year
2009
Total Cost
$340,559
Indirect Cost

  Institution

Name
University of California San Francisco
Department
Type
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143

  Publications

Peng, Annie R; Schnoll, Robert; Hawk Jr, Larry W et al. (2018) Predicting smoking abstinence with biological and self-report measures of adherence to varenicline: Impact on pharmacogenetic trial outcomes. Drug Alcohol Depend 190:72-81
Taghavi, Taraneh; Novalen, Maria; Lerman, Caryn et al. (2018) A Comparison of Direct and Indirect Analytical Approaches to Measuring Total Nicotine Equivalents in Urine. Cancer Epidemiol Biomarkers Prev 27:882-891
Chenoweth, Meghan J; Ware, Jennifer J; Zhu, Andy Z X et al. (2018) Genome-wide association study of a nicotine metabolism biomarker in African American smokers: impact of chromosome 19 genetic influences. Addiction 113:509-523
Tanner, Julie-Anne; Zhu, Andy Z; Claw, Katrina G et al. (2018) Novel CYP2A6 diplotypes identified through next-generation sequencing are associated with in-vitro and in-vivo nicotine metabolism. Pharmacogenet Genomics 28:7-16
Ware, Jennifer J; Tanner, Julie-Anne; Taylor, Amy E et al. (2017) Does coffee consumption impact on heaviness of smoking? Addiction 112:1842-1853
Ashare, Rebecca L; Lerman, Caryn; Tyndale, Rachel F et al. (2017) Sleep Disturbance During Smoking Cessation: Withdrawal or Side Effect of Treatment? J Smok Cessat 12:63-70
Tanner, Julie-Anne; Prasad, Bhagwat; Claw, Katrina G et al. (2017) Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. J Pharmacol Exp Ther 360:129-139
Goodman, Michelle S; Bridgman, Alanna C; Rabin, Rachel A et al. (2017) Differential effects of cannabis dependence on cortical inhibition in patients with schizophrenia and non-psychiatric controls. Brain Stimul 10:275-282
Schuit, Ewoud; Panagiotou, Orestis A; Munafò, Marcus R et al. (2017) Pharmacotherapy for smoking cessation: effects by subgroup defined by genetically informed biomarkers. Cochrane Database Syst Rev 9:CD011823
Chenoweth, Meghan J; Tyndale, Rachel F (2017) Pharmacogenetic Optimization of Smoking Cessation Treatment. Trends Pharmacol Sci 38:55-66

Showing the most recent 10 out of 165 publications