Abstract

The San Antonio consortium for Research on Incontinence and urinary Dysfunction (SARID) is a multi-institutional study designed to compare in a prospective, randomized clinical trial, the two most effective treatments for Stress Urinary Incontinence due to urethral hypermobility (SUI-UH). Female patients with SUI-UH will undergo rigorous pre-treatment evaluation to ensure a diagnosis of SUI-UH and will be followed closely to assess not only the control of SUI but also a variety of important quality of life parameters. SARlD will also evaluate those factors that predict the long- term success of surgical management of SUI-UH, including factors that are very common in the South Texas Hispanic population including diabetes mellitus. The San Antonio consortium plans to accrue patients from military, Veterans Administration, and the general metropolitan San Antonio region, including a large number of underserved and minority patients to allow an evaluation of the efficacy of treatments among these different populations.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01DK058234-05
Application #
6799604
Study Section
Special Emphasis Panel (ZDK1-GRB-B (M1))
Program Officer
Kusek, John W
Project Start
2000-09-30
Project End
2006-09-29
Budget Start
2004-07-01
Budget End
2006-09-29
Support Year
5
Fiscal Year
2004
Total Cost
$324,968
Indirect Cost

  Institution

Name
University of Texas Health Science Center San Antonio
Department
Urology
Type
Schools of Medicine
DUNS #
800772162
City
San Antonio
State
TX
Country
United States
Zip Code
78229

  Publications

Thomas-White, Krystal J; Kliethermes, Stephanie; Rickey, Leslie et al. (2017) Evaluation of the urinary microbiota of women with uncomplicated stress urinary incontinence. Am J Obstet Gynecol 216:55.e1-55.e16
Norton, Peggy A; Nager, Charles W; Brubaker, Linda et al. (2016) The cost of preoperative urodynamics: A secondary analysis of the ValUE trial. Neurourol Urodyn 35:81-4
Zimmern, Philippe E; Gormley, E Ann; Stoddard, Anne M et al. (2016) Management of recurrent stress urinary incontinence after burch and sling procedures. Neurourol Urodyn 35:344-8
Kenton, Kimberly; Stoddard, Anne M; Zyczynski, Halina et al. (2015) 5-year longitudinal followup after retropubic and transobturator mid urethral slings. J Urol 193:203-10
Guthrie, Katherine A; LaCroix, Andrea Z; Ensrud, Kristine E et al. (2015) Pooled Analysis of Six Pharmacologic and Nonpharmacologic Interventions for Vasomotor Symptoms. Obstet Gynecol 126:413-22
Sirls, Larry T; Tennstedt, Sharon; Brubaker, Linda et al. (2015) The minimum important difference for the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form in women with stress urinary incontinence. Neurourol Urodyn 34:183-7
Zyczynski, Halina M; Albo, Michael E; Goldman, Howard B et al. (2015) Change in Overactive Bladder Symptoms After Surgery for Stress Urinary Incontinence in Women. Obstet Gynecol 126:423-30
Brubaker, Linda; Litman, Heather J; Kim, Hae-Young et al. (2015) Missing data frequency and correlates in two randomized surgical trials for urinary incontinence in women. Int Urogynecol J 26:1155-9
Mueller, Elizabeth R; Litman, Heather; Rickey, Leslie R et al. (2015) Comparison of flowrates and voided volumes during non-instrumented uroflowmetry and pressure-flow studies in women with stress incontinence. Neurourol Urodyn 34:549-53
Zimmern, Philippe; Litman, Heather J; Nager, Charles W et al. (2014) Effect of aging on storage and voiding function in women with stress predominant urinary incontinence. J Urol 192:464-8

Showing the most recent 10 out of 74 publications