Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD021970-06
Application #
3552535
Study Section
Special Emphasis Panel (SRC)
Project Start
1986-09-01
Project End
1991-08-31
Budget Start
1990-12-01
Budget End
1991-08-31
Support Year
6
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Jackson Laboratory
Department
Type
DUNS #
042140483
City
Bar Harbor
State
ME
Country
United States
Zip Code
04609
Wigglesworth, Karen; Lee, Kyung-Bon; Emori, Chihiro et al. (2015) Transcriptomic diversification of developing cumulus and mural granulosa cells in mouse ovarian follicles. Biol Reprod 92:23
Lee, Kyung-Bon; Zhang, Meijia; Sugiura, Koji et al. (2013) Hormonal coordination of natriuretic peptide type C and natriuretic peptide receptor 3 expression in mouse granulosa cells. Biol Reprod 88:42
Robinson, Jerid W; Zhang, Meijia; Shuhaibar, Leia C et al. (2012) Luteinizing hormone reduces the activity of the NPR2 guanylyl cyclase in mouse ovarian follicles, contributing to the cyclic GMP decrease that promotes resumption of meiosis in oocytes. Dev Biol 366:308-16
Zhang, Meijia; Su, You-Qiang; Sugiura, Koji et al. (2011) Estradiol promotes and maintains cumulus cell expression of natriuretic peptide receptor 2 (NPR2) and meiotic arrest in mouse oocytes in vitro. Endocrinology 152:4377-85
Su, You-Qiang; Sugiura, Koji; Li, Qinglei et al. (2010) Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling. Mol Endocrinol 24:1230-9
Zhang, Meijia; Su, You-Qiang; Sugiura, Koji et al. (2010) Granulosa cell ligand NPPC and its receptor NPR2 maintain meiotic arrest in mouse oocytes. Science 330:366-9
Sugiura, Koji; Su, You-Qiang; Li, Qinglei et al. (2010) Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15. Mol Endocrinol 24:2303-14
Salisbury, Jesse; Hutchison, Keith W; Wigglesworth, Karen et al. (2009) Probe-level analysis of expression microarrays characterizes isoform-specific degradation during mouse oocyte maturation. PLoS One 4:e7479
Su, You-Qiang; Sugiura, Koji; Eppig, John J (2009) Mouse oocyte control of granulosa cell development and function: paracrine regulation of cumulus cell metabolism. Semin Reprod Med 27:32-42
Eppig, J J; O'Brien, M J; Wigglesworth, K et al. (2009) Effect of in vitro maturation of mouse oocytes on the health and lifespan of adult offspring. Hum Reprod 24:922-8

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