Abstract

The Adolescent AIDS Program (AAP) at Montefiore Medical Center of the Albert Einstein College of Medicine in the Bronx, New York is applying to be an Adolescent Medicine Trials Unit (AMTU) in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN). The AAP has more than a decade of experience and leadership in providing the highest quality clinical care and research with HIV-positive and at-risk youth. The AAP is located in the Bronx, New York, a locale with very high rate of HIV and other sexually transmitted infections. The AAP has a demonstrated ability yo maintain a cohort of more than one hundred HIV-positive youth (more than 225 cumulatively), the majority of whom have acquired HIV infection through sexual behaviors, and mostly youth of color, as well as a cohort of more than four hundred at-risk sexually experienced youth. The AAP has engaged more than one hundred HIV-positive youth and more than one hundred HIV-positive youth and more than 1000-HIV negative youth in clinical research in more than ten multi-site studies, including course of HIV disease (REACH, NIH), clinical trials (ACTG, NIH), behavioral interventions (TLC, CLEAR, NIH), risk behavior analyses (CDC) and others. The AAP plans to be an active and effective AMTU based on the following three components: 1) an experienced Principal Investigator and three Study Coordinators who have built and maintained the second most active site in the Adolescent Medicine HIV/AIDS Research Network, in addition to a long history as a Pediatric AIDS Clinical Trial Unit and experience in other multi-site studies; 20 a well-coordinated comprehensive care team started by medical and mental health practitioners experienced in HIV care and adolescent health; and 3) an innovative community outreach program, including the successful social marketing campaign """"""""HIV. Live with it. Get Tested."""""""", with strong relationships with community agencies serving at risk adolescents. Thus, the AAP will offer important scientific and operational contributions in meeting the research agenda posed in the Request for Applications by the National Institutes of Health.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project--Cooperative Agreements (U01)
Project #
5U01HD040499-02
Application #
6530571
Study Section
Special Emphasis Panel (ZHD1-DRG-D (02))
Program Officer
Willoughby, Anne
Project Start
2001-04-16
Project End
2006-02-28
Budget Start
2002-03-01
Budget End
2003-02-28
Support Year
2
Fiscal Year
2002
Total Cost
$565,620
Indirect Cost

  Institution

Name
Montefiore Medical Center (Bronx, NY)
Department
Type
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10467

  Publications

Boyer, Cherrie B; Greenberg, Lauren; Chutuape, Kate et al. (2017) Exchange of Sex for Drugs or Money in Adolescents and Young Adults: An Examination of Sociodemographic Factors, HIV-Related Risk, and Community Context. J Community Health 42:90-100
Nichols, Sharon L; Bethel, James; Kapogiannis, Bill G et al. (2016) Antiretroviral treatment initiation does not differentially alter neurocognitive functioning over time in youth with behaviorally acquired HIV. J Neurovirol 22:218-30
Futterman, Donna; Stafford, Stephen; Meissner, Paul et al. (2016) Ten Sites, 10 Years, 10 Lessons: Scale-up of Routine HIV Testing at Community Health Centers in the Bronx, New York. Public Health Rep 131 Suppl 1:53-62
Hanna, David B; Felsen, Uriel R; Ginsberg, Mindy S et al. (2016) Increased Antiretroviral Therapy Use and Virologic Suppression in the Bronx in the Context of Multiple HIV Prevention Strategies. AIDS Res Hum Retroviruses 32:955-963
Chutuape, Kate S; Willard, Nancy; Walker, Bendu C et al. (2015) A Tailored Approach to Launch Community Coalitions Focused on Achieving Structural Changes: Lessons Learned From a HIV Prevention Mobilization Study. J Public Health Manag Pract 21:546-55
Boyer, Cherrie B; Hightow-Weidman, Lisa; Bethel, James et al. (2013) An assessment of the feasibility and acceptability of a friendship-based social network recruitment strategy to screen at-risk African American and Hispanic/Latina young women for HIV infection. JAMA Pediatr 167:289-96
Lee, Sonia; Kapogiannis, Bill G; Flynn, Patricia M et al. (2013) Comprehension of a simplified assent form in a vaccine trial for adolescents. J Med Ethics 39:410-2
Doll, Mimi; Harper, Gary W; Robles-Schrader, Grisel M et al. (2012) Perspectives of community partners and researchers about factors impacting coalition functioning over time. J Prev Interv Community 40:87-102
Robles-Schrader, Grisel M; Harper, Gary W; Purnell, Marjorie et al. (2012) Differential challenges in coalition building among HIV prevention coalitions targeting specific youth populations. J Prev Interv Community 40:131-48
Willard, Nancy; Chutuape, Kate; Stines, Stephanie et al. (2012) Bridging the gap between individual-level risk for HIV and structural determinants: using root cause analysis in strategic planning. J Prev Interv Community 40:103-17

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