This proposal seeks support for a replication of the National Comorbidity Survey to be carried out in the year 2000, a decade after the original NCS. If funded, the replication survey would be administered to a new sample of 10,000 respondents in the age range 15 plus in conjunction with an already funded NIDA- supported reinterview survey of the original respondents in the NCS sample. There are two specific aims. The first is to investigate time trends and their correlates over the decade between the two surveys. We will investigate trends in both the lifetime prevalences (so-called """"""""cohort effects"""""""") of DSM disorders and in recent prevalences of these disorders. We will examine sociodemographic correlates of these trends, such as the possibilities that the sex difference in depression has decreased over the last decade and that the mental health gap between rich and poor people has increased. We will also examine trends in patterns of service use for these disorders, focusing on changes in the proportion of people with disorders in treatment, in the distribution of treatment across service sectors, in treatment intensity and adequacy, and in treatment dropout. We will also examine trends in a number of policy-relevant predictors of seeking treatment, including perceived need, perceived efficacy of treatment, and barriers to seeking treatment. The second specific aim is to generate nationally representative data for the U.S. in the year 2000 that will be used as part of the World Health Organization's (WHO) World Mental Health 2000 (WMH2000) Initiative. Under this aim we will coordinate with investigators in a dozen other countries around the world who are working with the WHO to carry out mental health needs assessment surveys in the year 2000. The surveys will ask parallel questions about the 12-month prevalences of seriously impairing and persistent mental disorders, treatment of these disorders, and the sociodemographic correlates of disorders and treatment. We will also estimate the societal costs of mental disorders from the perspective of the ill person, their employers, and the total society. A public use dataset that can be accessed by many students, researchers, and health policy analysts who need benchmark data of the sort provided by the proposed survey will be prepared and made available as soon as the data are collected and cleaned. In conjunction with the data release we will hold summer workshops in the use of the public dataset for two years after release.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Research Project--Cooperative Agreements (U01)
Project #
Application #
Study Section
Special Emphasis Panel (ZMH1-CRB-X (04))
Program Officer
Colpe, Lisa J
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Harvard University
Schools of Medicine
United States
Zip Code
Degenhardt, Louisa; Glantz, Meyer; Bharat, Chrianna et al. (2018) The impact of cohort substance use upon likelihood of transitioning through stages of alcohol and cannabis use and use disorder: Findings from the Australian National Survey on Mental Health and Wellbeing. Drug Alcohol Rev 37:546-556
Eun, John David; Paksarian, Diana; He, Jian-Ping et al. (2018) Parenting style and mental disorders in a nationally representative sample of US adolescents. Soc Psychiatry Psychiatr Epidemiol 53:11-20
Degenhardt, Louisa; Saha, Sukanta; Lim, Carmen C W et al. (2018) The associations between psychotic experiences and substance use and substance use disorders: findings from the World Health Organization World Mental Health surveys. Addiction 113:924-934
Alonso, Jordi; Liu, Zhaorui; Evans-Lacko, Sara et al. (2018) Treatment gap for anxiety disorders is global: Results of the World Mental Health Surveys in 21 countries. Depress Anxiety 35:195-208
Rosellini, A J; Liu, H; Petukhova, M V et al. (2018) Recovery from DSM-IV post-traumatic stress disorder in the WHO World Mental Health surveys. Psychol Med 48:437-450
Trevino, Kelly M; Prigerson, Holly G; Maciejewski, Paul K (2018) Advanced cancer caregiving as a risk for major depressive episodes and generalized anxiety disorder. Psychooncology 27:243-249
Kessler, R C; Aguilar-Gaxiola, S; Alonso, J et al. (2018) The associations of earlier trauma exposures and history of mental disorders with PTSD after subsequent traumas. Mol Psychiatry 23:1-8
de Jonge, Peter; Wardenaar, Klaas J; Lim, Carmen C W et al. (2018) The cross-national structure of mental disorders: results from the World Mental Health Surveys. Psychol Med 48:2073-2084
Scott, Kate M; Saha, Sukanta; Lim, Carmen C W et al. (2018) Psychotic experiences and general medical conditions: a cross-national analysis based on 28 002 respondents from 16 countries in the WHO World Mental Health Surveys. Psychol Med 48:2730-2739
Scott, K M; Koenen, K C; King, A et al. (2018) Post-traumatic stress disorder associated with sexual assault among women in the WHO World Mental Health Surveys. Psychol Med 48:155-167

Showing the most recent 10 out of 321 publications