Abstract

This program is to help support the participation of the Pediatric Oncology group at the University of Oregon Health Sciences Center in the Children's Cancer Study Group. The Pediatric Oncology program is a multidiscipline group formed to improve the quality of care of children with cancer in Oregon and adjacent states. The program includes four major commitments: 1) Patient care, 2) research, 3) teaching, and 4) continuing education of the public and health care professionals. Although this program deals primarily with patient care and research as it relates to patient care, all aspects of the program are interrelated and thus described in the text. The basic aim of the proposal is to provide for clinical research utilizing the patient population in this geographic area by participating in Children's Cancer Study Group treatment and protocols. Emphasis is placed on combining the best of multidisciplinary cancer therapy with strong psychosocial support for the patient and the family.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10CA026044-11
Application #
3556790
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1979-07-01
Project End
1993-11-30
Budget Start
1988-12-01
Budget End
1989-11-30
Support Year
11
Fiscal Year
1989
Total Cost
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Neudorf, Steven; Sanders, Jean; Kobrinsky, Nathan et al. (2004) Allogeneic bone marrow transplantation for children with acute myelocytic leukemia in first remission demonstrates a role for graft versus leukemia in the maintenance of disease-free survival. Blood 103:3655-61
Shamberger, Robert C; LaQuaglia, Michael P; Gebhardt, Mark C et al. (2003) Ewing sarcoma/primitive neuroectodermal tumor of the chest wall: impact of initial versus delayed resection on tumor margins, survival, and use of radiation therapy. Ann Surg 238:563-7; discussion 567-8
Davies, Stella M; Bhatia, Smita; Ross, Julie A et al. (2002) Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia. Blood 100:67-71
Lange, Beverly J; Bostrom, Bruce C; Cherlow, Joel M et al. (2002) Double-delayed intensification improves event-free survival for children with intermediate-risk acute lymphoblastic leukemia: a report from the Children's Cancer Group. Blood 99:825-33
Ou, Shu Xiao; Han, Dehui; Severson, Richard K et al. (2002) Birth characteristics, maternal reproductive history, hormone use during pregnancy, and risk of childhood acute lymphocytic leukemia by immunophenotype (United States). Cancer Causes Control 13:15-25
Cooper, R; Khakoo, Y; Matthay, K K et al. (2001) Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: histopathologic features-a report from the Children's Cancer Group. Med Pediatr Oncol 36:623-9
Meyers, P A; Krailo, M D; Ladanyi, M et al. (2001) High-dose melphalan, etoposide, total-body irradiation, and autologous stem-cell reconstitution as consolidation therapy for high-risk Ewing's sarcoma does not improve prognosis. J Clin Oncol 19:2812-20
Sposto, R; Meadows, A T; Chilcote, R R et al. (2001) Comparison of long-term outcome of children and adolescents with disseminated non-lymphoblastic non-Hodgkin lymphoma treated with COMP or daunomycin-COMP: A report from the Children's Cancer Group. Med Pediatr Oncol 37:432-41