Abstract

This is a proposal for the participation of St. Jude Children's Research Hospital (SJCRH) in the Pediatric Oncology Group (POG). The overall aim of this participation is to improve the treatment of children with cancer and to improve through collaborative studies our understanding of childhood cancer. The participation of SJCRH in the POG will include: 1) continued performance of independent studies which may develop into group wide studies, 2) collaborative laboratory studies involving biologic questions in childhood cancer, 3) contributing patients to selected group studies, and 4) cooperating in a major way in scientific and developmental activities in the group by committee participation and study design.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA031566-06
Application #
3557160
Study Section
Cancer Clinical Investigation Review Committee (CCI)
Project Start
1982-01-01
Project End
1990-12-31
Budget Start
1987-01-01
Budget End
1987-12-31
Support Year
6
Fiscal Year
1987
Total Cost
Indirect Cost

  Institution

Name
St. Jude Children's Research Hospital
Department
Type
DUNS #
067717892
City
Memphis
State
TN
Country
United States
Zip Code
38105

  Publications

Crews, Kristine R; Zhou, Yinmei; Pauley, Jennifer L et al. (2010) Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia. Cancer 116:227-32
Wacker, Pierre; Land, Vita J; Camitta, Bruce M et al. (2007) Allergic reactions to E. coli L-asparaginase do not affect outcome in childhood B-precursor acute lymphoblastic leukemia: a Children's Oncology Group Study. J Pediatr Hematol Oncol 29:627-32
Gadner, H; Masera, G; Schrappe, M et al. (2006) The Eighth International Childhood Acute Lymphoblastic Leukemia Workshop ('Ponte di legno meeting') report: Vienna, Austria, April 27-28, 2005. Leukemia 20:9-17
Arico, M; Baruchel, A; Bertrand, Y et al. (2005) The seventh international childhood acute lymphoblastic leukemia workshop report: Palermo, Italy, January 29--30, 2005. Leukemia 19:1145-52
Whitehead, V M; Shuster, J J; Vuchich, M J et al. (2005) Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukemia: a Pediatric Oncology Group study. Leukemia 19:533-6
Crews, Kristine R; Stewart, Clinton F; Liu, Tiebin et al. (2004) Effect of fractionated ifosfamide on the pharmacokinetics of irinotecan in pediatric patients with osteosarcoma. J Pediatr Hematol Oncol 26:764-7
Pui, C-H; Schrappe, M; Masera, G et al. (2004) Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop. Leukemia 18:1043-53
Crews, Kristine R; Liu, Tiebin; Rodriguez-Galindo, Carlos et al. (2004) High-dose methotrexate pharmacokinetics and outcome of children and young adults with osteosarcoma. Cancer 100:1724-33
Pui, C-H; Chessells, J M; Camitta, B et al. (2003) Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements. Leukemia 17:700-6
Shamberger, Robert C; LaQuaglia, Michael P; Gebhardt, Mark C et al. (2003) Ewing sarcoma/primitive neuroectodermal tumor of the chest wall: impact of initial versus delayed resection on tumor margins, survival, and use of radiation therapy. Ann Surg 238:563-7; discussion 567-8

Showing the most recent 10 out of 117 publications