The Iowa Oncology Research Association over the past four years has developed a multidisciplinary organization capable of carrying out high quality clinical cancer research in a community setting. Our potential for future performance as a CCOP is clearly demonstrated by our past and present performance. The Iowa Oncology Research Association has established its ability to productively join medical oncology, surgical oncology, radiation oncology, pathology, and cancer nursing into a cohesive clinical research unit in Des Moines. We have already established our ability to generate data of excellent quality and to place significant numbers of community patients on high priority, nationally approved clinical research protocols. We are the only source for bringing the benefits of the National Cancer Program to a large segment of this country's population. Specifically, the objectives of this application are to bring the advantages of clinical research to the cancer patients of central Iowa, to participate in nationally approved clinical research protocols, to reduce cancer mortality in our region by speeding transfer of newly developed cancer treatment technology to widespread community application, and to establish the foundation for participation of our region in future cancer control and cancer prevention research activities. These objectives will be accomplished by the already developed and functioning relationships between the Iowa Oncology Research Association CCOP and its research base, i.e., the Mayo Clinic through the medium of the North Central Cancer Treatment Group and as an intermediate to the Eastern Cooperative Oncology Group and the Children's Cancer Study Group. We would confidently predict that on the basis of our past performance and the potential for clinical research existing with the Iowa Oncology Research Association that we will enter at least 100 patients per annum on the research protocols provided through these research bases. By virtue of our established programs and those programs under active development we can confidently predict an equally productive involvement of the Iowa Oncology Research Association CCOP in cancer control research programs.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10CA035101-03S1
Application #
3557482
Study Section
(SRC)
Project Start
1983-09-15
Project End
1987-05-31
Budget Start
1985-09-01
Budget End
1987-05-31
Support Year
3
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Iowa Oncology Research Association
Department
Type
DUNS #
180870891
City
Des Moines
State
IA
Country
United States
Zip Code
50309
Barton, Debra L; Sloan, Jeff A; Shuster, Lynne T et al. (2018) Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance). Support Care Cancer 26:643-650
Schild, Steven E; Hillman, Shauna L; Tan, Angelina D et al. (2017) Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non-Small Cell Lung Cancer: NCCTG N0028 (Alliance). J Thorac Oncol 12:697-703
Liu, Xiaonan; Li, Jing; Schild, Steven E et al. (2017) Statins and Metformin Use Is Associated with Lower PSA Levels in Prostate Cancer Patients Presenting for Radiation Therapy. J Cancer Ther 8:73-85
Sio, Terence T; Atherton, Pamela J; Birckhead, Brandon J et al. (2016) Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]). Support Care Cancer 24:3847-55
Liu, Xiaonan; Li, Jing; Wu, Teresa et al. (2016) Patient Specific Characteristics Are an Important Factor That Determines the Risk of Acute Grade ? 2 Rectal Toxicity in Patients Treated for Prostate Cancer with IMRT and Daily Image Guidance Based on Implanted Gold Markers. OMICS J Radiol 5:
Pachman, Deirdre R; Qin, Rui; Seisler, Drew et al. (2016) Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer 24:5059-5068
Park, Haeseong; Qin, Rui; Smith, Thomas J et al. (2015) North Central Cancer Treatment Group N10C2 (Alliance): a double-blind placebo-controlled study of magnesium supplements to reduce menopausal hot flashes. Menopause 22:627-32
Rule, William G; Foster, Nathan R; Meyers, Jeffrey P et al. (2015) Prophylactic cranial irradiation in elderly patients with small cell lung cancer: findings from a North Central Cancer Treatment Group pooled analysis. J Geriatr Oncol 6:119-26
Van Loon, Katherine; Espinoza, Anne M; Fogelman, David R et al. (2014) Should combination chemotherapy serve as the backbone in clinical trials of advanced pancreatic cancer? A pooled analysis of phase II trials of gemcitabine-containing doublets plus bevacizumab. Pancreas 43:343-9
Dronca, Roxana S; Allred, Jacob B; Perez, Domingo G et al. (2014) Phase II study of temozolomide (TMZ) and everolimus (RAD001) therapy for metastatic melanoma: a North Central Cancer Treatment Group study, N0675. Am J Clin Oncol 37:369-76

Showing the most recent 10 out of 161 publications