The Grand Rapids Community Clinical Oncology Program is a consortium effort built upon a six-year history of cooperative effort in cancer control through the Grand Rapids Clinical Oncology Program. The present effort binds together the five acute care hospitals in Grand Rapids, Michigan and includes ten medical oncologists, four radiation oncologists, three oncology specialists (surgical, gynecological, immunological) and four hematologists in a cooperative consortium organization devoted to clinical research. The SOUTHWEST ONCOLOGY GROUP (SWOG) has been selected as our major research base (145 cases) with secondary affiliation with the Comprehensive Cancer Center of Metropolitan Detroit (CCCMD) - Wayne State University (15 cases); the National Surgical Adjuvant Breast and Bowel Project (NSABBP) (34 cases) and the Radiation Therapy Oncology Group (RTOG) (16 cases). Two thousand eight hundred and forty three new cases of cancer were diagnosed in the Kent County area in 1981, approximately 1,500 of which were referred to the CCOP team. Our total pledge of 211 cases for clinical trials is, we believe, an enthusiastic but conservative estimate of our ability to serve as a resource for clinical research. The proposed organizational structure represents what we feel is a realistic solution to the problems of operating a five-hospital, multi-investigator program. Our cost per case is $513, which we feel will be among the more economically efficient CCOP applicants. The Grand Rapids CCOP proposes a cost-efficient, community consortium capable of making a significant contribution, in quality and quantity to the national clinical research effort, at the same time, improving the delivery of optimum cancer care to the patients in our care.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA035178-03
Application #
3557577
Study Section
(SRC)
Project Start
1983-09-30
Project End
1987-05-31
Budget Start
1985-09-01
Budget End
1987-05-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Butterworth Hospital
Department
Type
DUNS #
City
Grand Rapids
State
MI
Country
United States
Zip Code
49503
Cheng, Heather H; Plets, Melissa; Li, Hongli et al. (2018) Circulating microRNAs and treatment response in the Phase II SWOG S0925 study for patients with new metastatic hormone-sensitive prostate cancer. Prostate 78:121-127
Samlowski, Wolfram E; Moon, James; Witter, Merle et al. (2017) High frequency of brain metastases after adjuvant therapy for high-risk melanoma. Cancer Med 6:2576-2585
Ramanathan, Ramesh K; McDonough, Shannon L; Kennecke, Hagen F et al. (2015) Phase 2 study of MK-2206, an allosteric inhibitor of AKT, as second-line therapy for advanced gastric and gastroesophageal junction cancer: A SWOG cooperative group trial (S1005). Cancer 121:2193-7
Lee, Sylvia M; Moon, James; Redman, Bruce G et al. (2015) Phase 2 study of RO4929097, a gamma-secretase inhibitor, in metastatic melanoma: SWOG 0933. Cancer 121:432-440
Persky, Daniel O; Miller, Thomas P; Unger, Joseph M et al. (2015) Ibritumomab consolidation after 3 cycles of CHOP plus radiotherapy in high-risk limited-stage aggressive B-cell lymphoma: SWOG S0313. Blood 125:236-41
Goldkorn, Amir; Ely, Benjamin; Tangen, Catherine M et al. (2015) Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial. Int J Cancer 136:1856-62
Blumenthal, Deborah T; Rankin, Cathryn; Stelzer, Keith J et al. (2015) A Phase III study of radiation therapy (RT) and O?-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001. Int J Clin Oncol 20:650-8
Yu, Evan Y; Li, Hongli; Higano, Celestia S et al. (2015) SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer. J Clin Oncol 33:1601-8
Othus, Megan; Appelbaum, Frederick R; Petersdorf, Stephen H et al. (2015) Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy. Biol Blood Marrow Transplant 21:559-64
Budd, George T; Barlow, William E; Moore, Halle C F et al. (2015) SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol 33:58-64

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