This grant application requests support for Evanston Hospital's (EH) continued participation in the Community Clinical Oncology Program (CCOP). We have participated in the studies of the Eastern Cooperative Oncology Group (ECOG), Illinois Cancer Council (ICC), Radiation Therapy Oncology Group (RTOG), and Gynecology Oncology Group (GOG). Through the ICC, we have also contributed patients outside the CCOP in the studies of the Lung Cancer Study Group (LCSG), and in the past, the Gastrointestinal Study Group. This grant will insure continued participation in the studies of the ECOG, ICC, RTOG and GOG. The EH investigators have also chaired protocols in the ECOG study sections of Genitourinary and Breast Cancer. They have also chaired studies on brain tumors and cancers of breast, colon, and ovary developed by the ICC. The hospital has participated in a number of cancer control projects such as NCI and LCSG sponsored quality of life surveys, relationship of cholecystectomy to colon cancer, value of mass screening with hemocultt slides in the diagnosis of colon cancer, head and neck demonstration projects, thyroid recall clinic, etc. A geographically centralized multidisciplinary outpatient service has been in operation for the past 5 years. We have also designated medical and surgical oncology beds. EH investigators have also developed local protocols in regional hyperthermia, ambulatory/home chemotherapy, and more recently, phase I clinical studies with aminothiadiazole. These protocols, if found suitable, will be incorporated into groupwide studies. The patients will receive and participate in clinical trials including cancer control protocols within their own communities. We will continue to expand our educational role in the next few years. Thus, participation in the activities in the cancer control and in therapeutic clinical trials will lead to scientific advances and stimulate better patient care which, in turn, will favorably impact on the level of knowledge of the staff and physicians within the hospital and in the community. The prior successful participation of this hospital in CCOP and in the cancer control studies assures future success of this grant.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Cooperative Clinical Research--Cooperative Agreements (U10)
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Evanston Hospital
United States
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Cohee, Andrea A; Bigatti, Silvia M; Shields, Cleveland G et al. (2018) Quality of Life in Partners of Young and Old Breast Cancer Survivors. Cancer Nurs 41:491-497
Bhatia, Aarti K; Lee, Ju-Whei; Pinto, Harlan A et al. (2017) Double-blind, randomized phase 3 trial of low-dose 13-cis retinoic acid in the prevention of second primaries in head and neck cancer: Long-term follow-up of a trial of the Eastern Cooperative Oncology Group-ACRIN Cancer Research Group (C0590). Cancer 123:4653-4662
Cohee, Andrea A; Adams, Rebecca N; Fife, Betsy L et al. (2017) Relationship Between Depressive Symptoms and Social Cognitive Processing in Partners of Long-Term Breast Cancer Survivors. Oncol Nurs Forum 44:44-51
Cohee, Andrea A; Adams, Rebecca N; Johns, Shelley A et al. (2017) Long-term fear of recurrence in young breast cancer survivors and partners. Psychooncology 26:22-28
Cohee, Andrea A; Stump, Timothy; Adams, Rebecca N et al. (2016) Factors associated with depressive symptoms in young long-term breast cancer survivors. Qual Life Res 25:1991-7
Grinblatt, David L; Yu, Daohai; Hars, Vera et al. (2009) Treatment of myelodysplastic syndrome with 2 schedules and doses of oral topotecan: a randomized phase 2 trial by the Cancer and Leukemia Group B (CALGB 19803). Cancer 115:84-93
Dhodapkar, Madhav V; Hoering, Antje; Gertz, Morie A et al. (2009) Long-term survival in Waldenstrom macroglobulinemia: 10-year follow-up of Southwest Oncology Group-directed intergroup trial S9003. Blood 113:793-6
Locker, G Y; Kilton, L; Khandekar, J D et al. (1994) High-dose aminothiadiazole in advanced colorectal cancer. An Illinois Cancer Center phase II trial. Invest New Drugs 12:299-301