The St. Mary's/Duluth Clinic Health System (SMDC Health System) formerly known as the Duluth Clinic has worked for the past twenty three years to develop a multidisciplinary organization involved in the care of oncology patients and to function as a cancer research unit for the region. St. Mary's Medical Center, the only tertiary care hospital in our region, and Duluth Clinic, the largest multispecialty physician group practice in our region, merged in January 1997 to become SMDC Health System. The Duluth Clinic was a founding member of the North Central Cancer Treatment Group in 1977 and has functioned as a CCOP since 1984. During this time, the Duluth CCOP has entered patients onto numerous clinical trials, has assisted in the development of new programs, served as chair or co-chair on numerous protocols, and has presented at national meetings. An excellent working relationship exists with the cooperative groups and data of excellent quality is generated as shown by past audit performance records. Geographically, the Duluth CCOP is the main source providing the benefits of clinical cancer research to this large geographic area. The Northwestern Ontario Regional Cancer Centre, Ontario, Canada, a component of the Duluth CCOP covers a large area also. This is a unique relationship in that the two components are two separate cancer centers, have two separate patient populations and are in two different countries. Our strategy is to continuously offer the advantages of clinical research to patients in the catchment/service area and to increase efforts in cancer prevention, cancer control and cancer rehabilitation. The North Central Cancer Treatment Group functions as the primary research base and the secondary research bases are the Eastern Cooperative Oncology Group, the Children's Cancer Group, the National Surgical Adjuvant Breast and Bowel Project and just recently the Southwest Oncology Group. The goal of the CCOP is to accrue over 120 patients per year onto cancer treatment protocols and 200 patients to cancer prevention and control programs per year. By virtue of the already established programs and the commitment to quality, it is believed that a high level of productivity and quality can be maintained.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA035269-20
Application #
6632918
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Program Officer
Kelaghan, Joseph
Project Start
1983-09-01
Project End
2005-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
20
Fiscal Year
2003
Total Cost
$714,555
Indirect Cost
Name
Duluth Clinic, Ltd.
Department
Type
DUNS #
361078798
City
Duluth
State
MN
Country
United States
Zip Code
55805
Barton, Debra L; Sloan, Jeff A; Shuster, Lynne T et al. (2018) Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance). Support Care Cancer 26:643-650
Sio, Terence T; Atherton, Pamela J; Birckhead, Brandon J et al. (2016) Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]). Support Care Cancer 24:3847-55
Navari, Rudolph M; Qin, Rui; Ruddy, Kathryn J et al. (2016) Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting. N Engl J Med 375:134-42
Pachman, Deirdre R; Qin, Rui; Seisler, Drew et al. (2016) Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer 24:5059-5068
Dueck, A C; Singh, J; Atherton, P et al. (2015) Endpoint comparison for bone mineral density measurements in North Central Cancer Treatment Group cancer clinical trials N02C1 and N03CC (Alliance). Osteoporos Int 26:1971-7
Liu, Heshan; Tan, Angelina D; Qin, Rui et al. (2015) Comparing and Validating Simple Measures of Patient-Reported Peripheral Neuropathy for Oncology Clinical Trials: NCCTG N0897 (Alliance) A Pooled Analysis of 2440 Patients. SOJ Anesthesiol Pain Manag 2:
Wagner-Johnston, Nina D; Sloan, Jeff A; Liu, Heshan et al. (2015) 5-year follow-up of a randomized controlled trial of immediate versus delayed zoledronic acid for the prevention of bone loss in postmenopausal women with breast cancer starting letrozole after tamoxifen: N03CC (Alliance) trial. Cancer 121:2537-43
Dronca, Roxana S; Allred, Jacob B; Perez, Domingo G et al. (2014) Phase II study of temozolomide (TMZ) and everolimus (RAD001) therapy for metastatic melanoma: a North Central Cancer Treatment Group study, N0675. Am J Clin Oncol 37:369-76
Dy, Grace K; Molina, Julian R; Qi, Yingwei et al. (2014) NCCTG N0821 (Alliance): a phase II first-line study of pemetrexed, carboplatin, and bevacizumab in elderly patients with advanced nonsquamous non-small-cell lung cancer with good performance status. J Thorac Oncol 9:1146-53
Barton, Debra L; Thanarajasingam, Gita; Sloan, Jeff A et al. (2014) Phase III double-blind, placebo-controlled study of gabapentin for the prevention of delayed chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy, NCCTG N08C3 (Alliance). Cancer 120:3575-83

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