The Ochsner CCOP has been a continuously funded clinical research unit since 1983. From September 1, 1983 through May 31, 1999, 2815 cases have been placed on NCI approved clinical trials; 778 have been enrolled during the first four years of the current funding period. Ochsner CCOP Investigators have been awarded authorship on 70 cooperative group publications (see Literature Cited). This CCOP has successfully integrated the resources of a major medical center, Oschner Medical Institutions, with community based oncologists in the spirit of the CCOP RFA. Over the past several years of the CCOP's existence, the quality of cancer care in rural Louisiana and Mississippi has improved significantly which supports the NCI's diffusion hypothesis. The goals of the Ochsner CCOP for the new grant period are: 1. To sustain the strong accrual patterns and high-quality, timely data submission already established.; 2. To enhance accrual to cancer Prevention and Control protocols by increasing the involvement of community based primary care physicians and non-oncologist specialists; 3. To increase the involvement of young investigators who have recently joined the CCOP to assure the long-term viability of the CCOP; 4. To regularly review the menu of protocols to establish protocol priority to enhance investigator interest; 5. To monitor accrual patterns carefully to assure that minorities, women, and older patients have qual access to protocol participation; 6. To increase involvement of CCOP CRAs and oncology nurses in recruitment efforts for cancer control and prevention studies. The Ochsner CCOP will build on its proven track record as an efficient, disciplined clinical research team. The investigators are committed to continued involvement in all aspects of research base activities including memberships in disease-specific, modality, and administrative committees, as well as protocol chairmanships.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
2U10CA035272-17
Application #
6143910
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Project Start
1983-09-01
Project End
2005-05-31
Budget Start
2000-06-01
Budget End
2001-05-31
Support Year
17
Fiscal Year
2000
Total Cost
$531,345
Indirect Cost
Name
Ochsner Clinic Foundation
Department
Type
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70121
Himelstein, Andrew L; Foster, Jared C; Khatcheressian, James L et al. (2017) Effect of Longer-Interval vs Standard Dosing of Zoledronic Acid on Skeletal Events in Patients With Bone Metastases: A Randomized Clinical Trial. JAMA 317:48-58
Pachman, Deirdre R; Qin, Rui; Seisler, Drew et al. (2016) Comparison of oxaliplatin and paclitaxel-induced neuropathy (Alliance A151505). Support Care Cancer 24:5059-5068
Gonsalves, Wilson I; Mahoney, Michelle R; Sargent, Daniel J et al. (2014) Patient and tumor characteristics and BRAF and KRAS mutations in colon cancer, NCCTG/Alliance N0147. J Natl Cancer Inst 106:
Barton, Debra L; Thanarajasingam, Gita; Sloan, Jeff A et al. (2014) Phase III double-blind, placebo-controlled study of gabapentin for the prevention of delayed chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy, NCCTG N08C3 (Alliance). Cancer 120:3575-83
Leal, Alexis D; Qin, Rui; Atherton, Pamela J et al. (2014) North Central Cancer Treatment Group/Alliance trial N08CA-the use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled study. Cancer 120:1890-7
Huang, Jocelin; Nair, Suresh G; Mahoney, Michelle R et al. (2014) Comparison of FOLFIRI with or without cetuximab in patients with resected stage III colon cancer; NCCTG (Alliance) intergroup trial N0147. Clin Colorectal Cancer 13:100-9
Province, M A; Goetz, M P; Brauch, H et al. (2014) CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations. Clin Pharmacol Ther 95:216-27
Barton, Debra L; Burger, Kelli; Novotny, Paul J et al. (2013) The use of Ginkgo biloba for the prevention of chemotherapy-related cognitive dysfunction in women receiving adjuvant treatment for breast cancer, N00C9. Support Care Cancer 21:1185-92
Lavoie Smith, Ellen M; Barton, Debra L; Qin, Rui et al. (2013) Assessing patient-reported peripheral neuropathy: the reliability and validity of the European Organization for Research and Treatment of Cancer QLQ-CIPN20 Questionnaire. Qual Life Res 22:2787-99
Sticca, Robert P; Alberts, Steven R; Mahoney, Michelle R et al. (2013) Current use and surgical efficacy of laparoscopic colectomy in colon cancer. J Am Coll Surg 217:56-62; discussion 62-3

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