The Mayo Comprehensive Cancer Center will serve as the primary research base for CCOP's located in Peoria, Illinois; Des Moines, Iowa; Duluth, Minnesota; Fargo, North Dakota; and Sioux Falls, South Dakota. We will cooperate with these CCOP's in planning their program development and in providing outlets for entry of patients on nationally approved clinical cancer research protocols through direct referral to the Mayo Clinic and through the North Central Cancer Treatment Group. We will provide training and active support for their study assistants, data managers, oncology nurses, and other supporting personnel. We will maintain standard reporting procedures for surgery, pathology, and radiation therapy, and these will be regularly reviewed and upgraded when indicated. We will hold regular meetings with the CCOP's for review of ongoing research, planning of future research, and for related professional education. We will continue the rigid quality control procedures which have proved so successful in the past and upgrade these procedures as indicated. We will consistently monitor the quality of the CCOP's not only by continuous review of patient data sheets, pathology material, operative reports, and radiation therapy port films but also by periodic randomly scheduled site visits. At least twice annually we will conduct an overall review of the performance of each CCOP.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA037404-03
Application #
3558049
Study Section
(SRC)
Project Start
1983-09-15
Project End
1987-05-31
Budget Start
1985-09-01
Budget End
1987-05-31
Support Year
3
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Barton, Debra L; Sloan, Jeff A; Shuster, Lynne T et al. (2018) Evaluating the efficacy of vaginal dehydroepiandosterone for vaginal symptoms in postmenopausal cancer survivors: NCCTG N10C1 (Alliance). Support Care Cancer 26:643-650
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Schild, Steven E; Hillman, Shauna L; Tan, Angelina D et al. (2017) Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non-Small Cell Lung Cancer: NCCTG N0028 (Alliance). J Thorac Oncol 12:697-703
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Liu, Xiaonan; Li, Jing; Schild, Steven E et al. (2017) Statins and Metformin Use Is Associated with Lower PSA Levels in Prostate Cancer Patients Presenting for Radiation Therapy. J Cancer Ther 8:73-85
Kottschade, Lisa; Novotny, Paul; Lyss, Alan et al. (2016) Chemotherapy-induced nausea and vomiting: incidence and characteristics of persistent symptoms and future directions NCCTG N08C3 (Alliance). Support Care Cancer 24:2661-7
Sio, Terence T; Atherton, Pamela J; Birckhead, Brandon J et al. (2016) Repeated measures analyses of dermatitis symptom evolution in breast cancer patients receiving radiotherapy in a phase 3 randomized trial of mometasone furoate vs placebo (N06C4 [alliance]). Support Care Cancer 24:3847-55
Atherton, Pamela J; Burger, Kelli N; Pederson, Levi D et al. (2016) Patient-reported outcomes questionnaire compliance in Cancer Cooperative Group Trials (Alliance N0992). Clin Trials 13:612-620
Miller, Robert C; Petereit, Daniel G; Sloan, Jeff A et al. (2016) N08C9 (Alliance): A Phase 3 Randomized Study of Sulfasalazine Versus Placebo in the Prevention of Acute Diarrhea in Patients Receiving Pelvic Radiation Therapy. Int J Radiat Oncol Biol Phys 95:1168-74

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